3H5X

Crystal Structure of 2'-amino-2'-deoxy-cytidine-5'-triphosphate bound to Norovirus GII RNA polymerase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003968	molecular_function	RNA-dependent RNA polymerase activity
A	0004386	molecular_function	helicase activity
A	0005524	molecular_function	ATP binding
A	0006351	biological_process	DNA-templated transcription
A	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 511

Chain	Residue
A	TYR243
A	ASP343
A	CSG515
A	HOH882

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MN A 512

Chain	Residue
A	ASP343
A	CSG515
P	G8

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 513

Chain	Residue
A	HOH563
A	HOH637
A	ALA241
A	ASP344

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 514

Chain	Residue
A	ASP99
A	GLU205
A	HIS209
A	ASP289

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site_id	AC5
Number of Residues	18
Details	BINDING SITE FOR RESIDUE CSG A 515

Chain	Residue
A	ARG182
A	TYR243
A	SER244
A	ARG245
A	TRP246
A	ASP247
A	SER300
A	ASN309
A	ASP343
A	MN511
A	MN512
A	HOH738
A	HOH780
A	HOH816
A	HOH883
A	HOH884
P	G8
T	G2

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site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 516

Chain	Residue
A	ARG30
A	LEU36
A	ARG52
A	SER427
A	HOH635
A	HOH638

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site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 517

Chain	Residue
A	LEU169
A	ARG413
A	GLN414
A	TRP417
A	THR418
A	ARG419
A	HOH754
P	C5
P	G6

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site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 518

Chain	Residue
A	ALA256
A	GLU260
A	GLN273
A	HOH682

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site_id	AC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL T 509

Chain	Residue
A	THR117
A	LYS166
T	G2
T	C3
T	C4
T	HOH517
T	HOH721
T	HOH814
T	HOH896

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