8IIB
| Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta85 mutant (residues 86-546) | Descriptor: | CADMIUM ION, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Fang, X, Lu, G, Hou, C, Gong, P. | Deposit date: | 2023-02-24 | Release date: | 2023-06-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding. Virol Sin, 38, 2023
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8IIC
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6JIQ
| Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA dT6 | Descriptor: | DNA (5'-D(*TP*TP*TP*TP*T)-3'), SP_0782 | Authors: | Fang, X, Lu, G, Li, S, Zhu, J, Yang, Y, Gong, P. | Deposit date: | 2019-02-22 | Release date: | 2019-11-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structural insight into the length-dependent binding of ssDNA by SP_0782 from Streptococcus pneumoniae, reveals a divergence in the DNA-binding interface of PC4-like proteins. Nucleic Acids Res., 48, 2020
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6JIP
| Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA dT6 | Descriptor: | DNA (5'-D(*TP*TP*TP*TP*T)-3'), PENTAETHYLENE GLYCOL, SP_0782 | Authors: | Fang, X, Lu, G, Li, S, Zhu, J, Yang, Y, Gong, P. | Deposit date: | 2019-02-22 | Release date: | 2019-11-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.659 Å) | Cite: | Structural insight into the length-dependent binding of ssDNA by SP_0782 from Streptococcus pneumoniae, reveals a divergence in the DNA-binding interface of PC4-like proteins. Nucleic Acids Res., 48, 2020
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6M3A
| Staphylococcus aureus Bap-C1 | Descriptor: | Biofilm-associated surface protein | Authors: | Fang, X, Ning, X. | Deposit date: | 2020-03-03 | Release date: | 2021-04-07 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution structure of Staphylococcus aureus Bap_C1 To Be Published
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6NXJ
| Flavin Transferase ApbE from Vibrio cholerae, H257G mutant | Descriptor: | FAD:protein FMN transferase, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION | Authors: | Osipiuk, J, Fang, X, Chakravarthy, S, Juarez, O, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-02-08 | Release date: | 2019-03-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Conserved residue His-257 ofVibrio choleraeflavin transferase ApbE plays a critical role in substrate binding and catalysis. J.Biol.Chem., 294, 2019
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6NXI
| Flavin Transferase ApbE from Vibrio cholerae | Descriptor: | 1,2-ETHANEDIOL, FAD:protein FMN transferase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Osipiuk, J, Fang, X, Chakravarthy, S, Juarez, O, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-02-08 | Release date: | 2019-03-13 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Conserved residue His-257 ofVibrio choleraeflavin transferase ApbE plays a critical role in substrate binding and catalysis. J.Biol.Chem., 294, 2019
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7C7U
| Biofilm associated protein - BSP domain | Descriptor: | Biofilm-associated surface protein, CALCIUM ION | Authors: | Ma, J.F, Xu, Z.H, Zhang, Y.K, Cheng, X, Fan, S.L, Wang, J.W, Fang, X.Y. | Deposit date: | 2020-05-26 | Release date: | 2021-05-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structural mechanism for modulation of functional amyloid and biofilm formation by Staphylococcal Bap protein switch. Embo J., 40, 2021
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7C7R
| Biofilm associated protein - B domain | Descriptor: | Biofilm-associated surface protein, CALCIUM ION | Authors: | Ma, J.F, Xu, Z.H, Zhang, Y.K, Cheng, X, Fan, S.L, Wang, J.W, Fang, X.Y. | Deposit date: | 2020-05-26 | Release date: | 2021-05-12 | Last modified: | 2021-07-28 | Method: | X-RAY DIFFRACTION (3.07 Å) | Cite: | Structural mechanism for modulation of functional amyloid and biofilm formation by Staphylococcal Bap protein switch. Embo J., 40, 2021
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2LF0
| Solution structure of sf3636, a two-domain unknown function protein from Shigella flexneri 2a, determined by joint refinement of NMR, residual dipolar couplings and small-angle X-ray scattering, NESG target SfR339/OCSP target sf3636 | Descriptor: | Uncharacterized protein yibL | Authors: | Wu, B, Lemak, A, Yee, A, Lee, H, Gutmanas, A, Semesi, A, Garcia, M, Fang, X, Wang, Y, Prestegard, J.H, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP) | Deposit date: | 2011-06-27 | Release date: | 2011-07-13 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR, SOLUTION SCATTERING | Cite: | Solution structure of sf3636, a two-domain unknown function protein from Shigella flexneri 2a, determined by joint refinement of NMR, residual dipolar couplings and small-angle X-ray scattering To be Published
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8KFA
| Cryo-EM structure of HSV-1 gB with D48 Fab complex | Descriptor: | D48 heavy chain, D48 light chain, Envelope glycoprotein B | Authors: | Yang, J, Sun, C, Fang, X, Zeng, M, Liu, Z. | Deposit date: | 2023-08-15 | Release date: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | The structure of HSV-1 gB bound to a potent neutralizing antibody reveals a conservative antigenic domain across herpesviruses hlife, 2023
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7WII
| The THF-II riboswitch bound to NPR | Descriptor: | 2-AMINO-7,8-DIHYDRO-6-(1,2,3-TRIHYDROXYPROPYL)-4(1H)-PTERIDINONE, RNA (50-MER) | Authors: | Xu, L, Fang, X, Xiao, Y. | Deposit date: | 2022-01-03 | Release date: | 2023-01-18 | Last modified: | 2023-02-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural insights into translation regulation by the THF-II riboswitch. Nucleic Acids Res., 51, 2023
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7WIA
| The apo-form of THF-II C22G riboswitch | Descriptor: | RNA (50-MER) | Authors: | Xu, L, Fang, X, Xiao, Y. | Deposit date: | 2022-01-03 | Release date: | 2023-01-18 | Last modified: | 2023-02-08 | Method: | X-RAY DIFFRACTION (3.22 Å) | Cite: | Structural insights into translation regulation by the THF-II riboswitch. Nucleic Acids Res., 51, 2023
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7WI9
| The THF-II riboswitch bound to THF and soaking with SeUrea | Descriptor: | (6S)-5,6,7,8-TETRAHYDROFOLATE, RNA (50-MER), selenourea | Authors: | Xu, L, Fang, X, Xiao, Y. | Deposit date: | 2022-01-03 | Release date: | 2023-01-18 | Last modified: | 2023-02-08 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Structural insights into translation regulation by the THF-II riboswitch. Nucleic Acids Res., 51, 2023
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7WIE
| The THF-II riboswitch bound to 7DG | Descriptor: | 7-DEAZAGUANINE, RNA (50-MER) | Authors: | Xu, L, Fang, X, Xiao, Y. | Deposit date: | 2022-01-03 | Release date: | 2023-01-18 | Last modified: | 2023-02-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural insights into translation regulation by the THF-II riboswitch. Nucleic Acids Res., 51, 2023
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7WIB
| The THF-II riboswitch bound to THF | Descriptor: | (6S)-5,6,7,8-TETRAHYDROFOLATE, RNA (50-MER) | Authors: | Xu, L, Fang, X, Xiao, Y. | Deposit date: | 2022-01-03 | Release date: | 2023-01-18 | Last modified: | 2023-02-08 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Structural insights into translation regulation by the THF-II riboswitch. Nucleic Acids Res., 51, 2023
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7WIF
| The THF-II riboswitch bound to H4B | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, RNA (50-MER) | Authors: | Xu, L, Fang, X, Xiao, Y. | Deposit date: | 2022-01-03 | Release date: | 2023-01-18 | Last modified: | 2023-02-08 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Structural insights into translation regulation by the THF-II riboswitch. Nucleic Acids Res., 51, 2023
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7DM0
| Biofilm associated protein - C region | Descriptor: | Biofilm-associated surface protein, CALCIUM ION | Authors: | Ma, J.F, Fang, X.Y. | Deposit date: | 2020-12-01 | Release date: | 2021-12-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Biofilm associated protein - C region To Be Published
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4H42
| Synthesis of a Weak Basic uPA Inhibitor and Crystal Structure of Complex with uPA | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, N-[(2-amino-1,3-benzothiazol-6-yl)carbonyl]glycine, Urokinase-type plasminogen activator | Authors: | Yu, H.-Y, Gao, D, Zhang, X, Jiang, L.-G, Hong, Z.-B, Yuan, C, Fang, X, Wang, J.-D, Huang, M.-D. | Deposit date: | 2012-09-14 | Release date: | 2013-10-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Synthesis of a Weak Basic uPA Inhibitor and Crystal Structure of Complex with uPA CHIN.J.STRUCT.CHEM., 32, 2013
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