6JMA
 
 | | cryo-EM structure of DOT1L bound to H2B ubiquitinated nucleosome | | Descriptor: | DNA I&J, Histone H2A, Histone H2B 1.1, ... | | Authors: | Jang, S, Song, J.J. | | Deposit date: | 2019-03-07 | | Release date: | 2019-05-15 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (6.8 Å) | | Cite: | Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase.
Genes Dev., 33, 2019
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6TTU
 | | Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1 N98R-SKP1-monomeric b-TRCP1dD-IkBa-UB~UBE2D2 | | Descriptor: | CYS-LYS-LYS-ALA-ARG-HIS-ASP-SEP-GLY, Cullin-1, E3 ubiquitin-protein ligase RBX1, ... | | Authors: | Baek, K, Prabu, J.R, Schulman, B.A. | | Deposit date: | 2019-12-30 | | Release date: | 2020-02-12 | | Last modified: | 2020-03-04 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | NEDD8 nucleates a multivalent cullin-RING-UBE2D ubiquitin ligation assembly.
Nature, 578, 2020
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6KFP
 | | Crystal structure of MavC ternary complex | | Descriptor: | MavC, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 N | | Authors: | Mu, Y, Wang, Y, Han, Y, Li, D, Feng, Y. | | Deposit date: | 2019-07-08 | | Release date: | 2020-04-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.92 Å) | | Cite: | Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC.
Nat Commun, 11, 2020
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6KIV
 | | Cryo-EM structure of human MLL1-ubNCP complex (4.0 angstrom) | | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | | Authors: | Huang, J, Xue, H, Yao, T. | | Deposit date: | 2019-07-20 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
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6KIU
 | | Cryo-EM structure of human MLL1-ubNCP complex (3.2 angstrom) | | Descriptor: | DNA (145-MER), GLUTAMINE, Histone H2A, ... | | Authors: | Huang, J, Xue, H, Yao, T. | | Deposit date: | 2019-07-20 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
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6ULH
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6UMS
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6UH5
 | | Structural basis of COMPASS eCM recognition of the H2Bub nucleosome | | Descriptor: | Bre2, DNA (146-MER), H3 N-terminus, ... | | Authors: | Hsu, P.L, Shi, H, Zheng, N. | | Deposit date: | 2019-09-26 | | Release date: | 2019-11-20 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS.
Mol.Cell, 76, 2019
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5WYJ
 | | Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1) | | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ... | | Authors: | Ye, K, Zhu, X, Sun, Q. | | Deposit date: | 2017-01-13 | | Release date: | 2017-03-29 | | Last modified: | 2019-10-09 | | Method: | ELECTRON MICROSCOPY (8.7 Å) | | Cite: | Molecular architecture of the 90S small subunit pre-ribosome.
Elife, 6, 2017
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6KIW
 | | Cryo-EM structure of human MLL3-ubNCP complex (4.0 angstrom) | | Descriptor: | DNA (144-MER), DNA (145-MER), Histone H2A, ... | | Authors: | Huang, J, Xue, H, Yao, T. | | Deposit date: | 2019-07-20 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
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6KG6
 | | Crystal structure of MavC/UBE2N-Ub complex | | Descriptor: | MavC, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 N | | Authors: | Wang, Y, Huang, Y, Chang, M, Feng, Y. | | Deposit date: | 2019-07-10 | | Release date: | 2020-04-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC.
Nat Commun, 11, 2020
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6UMP
 | | Crystal structure of MavC in complex with substrate mimic in P65 space group | | Descriptor: | MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N | | Authors: | Puvar, K, Iyer, S, Luo, Z.Q, Das, C. | | Deposit date: | 2019-10-10 | | Release date: | 2020-05-27 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
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6UZ7
 | | K.lactis 80S ribosome with p/PE tRNA and eIF5B | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | | Authors: | Fernandez, I.S, Huang, B.Y. | | Deposit date: | 2019-11-14 | | Release date: | 2020-01-15 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Long-range interdomain communications in eIF5B regulate GTP hydrolysis and translation initiation.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6VEN
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6VEL
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6V9H
 | | Ankyrin repeat and SOCS-box protein 9 (ASB9), ElonginB (ELOB), and ElonginC (ELOC) bound to its substrate Brain-type Creatine Kinase (CKB) | | Descriptor: | Ankyrin repeat and SOCS box protein 9, Creatine kinase B-type, Elongin-B, ... | | Authors: | Komives, E.A, Lumpkin, R.J, Baker, R.W, Leschziner, A.E. | | Deposit date: | 2019-12-13 | | Release date: | 2020-04-29 | | Last modified: | 2020-11-11 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structure and dynamics of the ASB9 CUL-RING E3 Ligase.
Nat Commun, 11, 2020
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3J7P
 | | Structure of the 80S mammalian ribosome bound to eEF2 | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | Authors: | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | | Deposit date: | 2014-08-01 | | Release date: | 2014-09-03 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
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3JAM
 | | CryoEM structure of 40S-eIF1A-eIF1 complex from yeast | | Descriptor: | 18S rRNA, MAGNESIUM ION, RACK1, ... | | Authors: | Llacer, J.L, Hussain, T, Ramakrishnan, V. | | Deposit date: | 2015-06-17 | | Release date: | 2015-08-12 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.46 Å) | | Cite: | Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
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5XY3
 | | Large subunit of Trichomonas vaginalis ribosome | | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | Authors: | Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | | Deposit date: | 2017-07-06 | | Release date: | 2017-08-30 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
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3JAH
 | | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAG stop codon | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | Authors: | Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V. | | Deposit date: | 2015-06-10 | | Release date: | 2015-08-12 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
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3J6X
 | | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II) | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | | Authors: | Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A. | | Deposit date: | 2014-04-16 | | Release date: | 2014-06-11 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (6.1 Å) | | Cite: | Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
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5XXU
 | | Small subunit of Toxoplasma gondii ribosome | | Descriptor: | 18S RNA, Ribosomal protein eL41, Ribosomal protein eS1, ... | | Authors: | LI, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | | Deposit date: | 2017-07-05 | | Release date: | 2017-08-30 | | Last modified: | 2018-10-24 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
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6W2S
 | | Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal subunit in the open state (Class 1) | | Descriptor: | 18S rRNA, CrPV 5'-UTR IRES, Eukaryotic translation initiation factor 3 subunit A, ... | | Authors: | Neupane, R, Pisareva, V, Rodriguez, C.F, Pisarev, A, Fernandez, I.S. | | Deposit date: | 2020-03-08 | | Release date: | 2020-04-22 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate.
Elife, 9, 2020
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3K9O
 | | The crystal structure of E2-25K and UBB+1 complex | | Descriptor: | Ubiquitin, Ubiquitin-conjugating enzyme E2 K | | Authors: | Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H. | | Deposit date: | 2009-10-16 | | Release date: | 2010-09-08 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Basis of E2-25K/UBB+1 Interaction for Neurotoxicity of Alzheimer Disease by Proteasome Inhibition
To be Published
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3J80
 | | CryoEM structure of 40S-eIF1-eIF1A preinitiation complex | | Descriptor: | 18S rRNA, MAGNESIUM ION, RACK1, ... | | Authors: | Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V. | | Deposit date: | 2014-08-28 | | Release date: | 2014-11-05 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.75 Å) | | Cite: | Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
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