6VEL
Crystal Structure of Human E-cadherin bound by mouse monoclonal antibody 66E8Fab
Summary for 6VEL
Entry DOI | 10.2210/pdb6vel/pdb |
Descriptor | 66E8 Fab Heavy Chain, 66E8 Fab Light Chain, Ubiquitin-like protein SMT3,Cadherin-1, ... (6 entities in total) |
Functional Keywords | ssgcid, cadherin, e-cadherin, antibody, structural genomics, seattle structural genomics center for infectious disease, cell adhesion, cell adhesion-immune system complex, cell adhesion/immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 3 |
Total formula weight | 89540.77 |
Authors | Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2020-01-02, release date: 2020-01-29, Last modification date: 2023-10-25) |
Primary citation | Maker, A.,Bolejack, M.,Schecterson, L.,Hammerson, B.,Abendroth, J.,Edwards, T.E.,Staker, B.,Myler, P.J.,Gumbiner, B.M. Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography. Pnas Nexus, 1:pgac163-pgac163, 2022 Cited by PubMed: 36157596DOI: 10.1093/pnasnexus/pgac163 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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