6VEL
Crystal Structure of Human E-cadherin bound by mouse monoclonal antibody 66E8Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H | 66E8 Fab Heavy Chain | polymer | 243 | 26407.8 | 1 | Mus musculus | ||
2 | L | 66E8 Fab Light Chain | polymer | 233 | 25810.7 | 1 | Mus musculus | ||
3 | C | Ubiquitin-like protein SMT3,Cadherin-1 | polymer | 331 | 36625.7 | 1 | UniProt (Q12306) UniProt (P12830) Pfam (PF00240) Pfam (PF00028) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | CAM 120/80,Epithelial cadherin,E-cadherin,Uvomorulin |
4 | H, L, C | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
5 | C | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
6 | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
C: 4 - 101 (UniProt: Q12306)
C: 102 - 318 (UniProt: P12830)
PDB | External Database | Details |
---|---|---|
Met -12 | - | expression tag |
Ala -11 | - | expression tag |
Ser -10 | - | expression tag |
Met -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
Ser 0 | - | expression tag |
Met 1 | - | expression tag |
Ala 2 | - | expression tag |
Ser 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 88844.2 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 696.6 | |
All* | Total formula weight | 89540.8 |