7YQ6
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![BU of 7yq6 by Molmil](/molmil-images/mine/7yq6) | human insulin receptor bound with A62 DNA aptamer | Descriptor: | IR-A62 aptamer, Isoform Short of Insulin receptor | Authors: | Kim, J, Yunn, N, Ryu, S, Cho, Y. | Deposit date: | 2022-08-05 | Release date: | 2022-11-09 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures. Nat Commun, 13, 2022
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7YQ5
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![BU of 7yq5 by Molmil](/molmil-images/mine/7yq5) | human insulin receptor bound with A62 DNA aptamer and insulin | Descriptor: | IR-A62 aptamer, Insulin A chain, Insulin, ... | Authors: | Kim, J, Yunn, N, Ryu, S, Cho, Y. | Deposit date: | 2022-08-05 | Release date: | 2022-11-09 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.27 Å) | Cite: | Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures. Nat Commun, 13, 2022
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8DTM
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![BU of 8dtm by Molmil](/molmil-images/mine/8dtm) | Cryo-EM structure of insulin receptor (IR) bound with S597 component 2 | Descriptor: | Insulin mimetic peptide S597 component 2, Insulin receptor | Authors: | Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E. | Deposit date: | 2022-07-26 | Release date: | 2022-09-07 | Last modified: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Activation of the insulin receptor by an insulin mimetic peptide. Nat Commun, 13, 2022
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8DTL
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![BU of 8dtl by Molmil](/molmil-images/mine/8dtl) | Cryo-EM structure of insulin receptor (IR) bound with S597 peptide | Descriptor: | Insulin mimetic peptide S597, Insulin receptor | Authors: | Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E. | Deposit date: | 2022-07-25 | Release date: | 2022-09-07 | Last modified: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (5.4 Å) | Cite: | Activation of the insulin receptor by an insulin mimetic peptide. Nat Commun, 13, 2022
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8AFP
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![BU of 8afp by Molmil](/molmil-images/mine/8afp) | Structure of fibronectin 2 and 3 of L1CAM at 3.0 Angstrom | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neural cell adhesion molecule L1 | Authors: | Guedez, G, Loew, C. | Deposit date: | 2022-07-18 | Release date: | 2023-03-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | X-ray structure and function of fibronectin domains two and three of the neural cell adhesion molecule L1. Faseb J., 37, 2023
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8AFO
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![BU of 8afo by Molmil](/molmil-images/mine/8afo) | Structure of fibronectin 2 and 3 of L1CAM at 2.0 Angstrom | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neural cell adhesion molecule L1 | Authors: | Guedez, G, Loew, C. | Deposit date: | 2022-07-18 | Release date: | 2023-03-08 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | X-ray structure and function of fibronectin domains two and three of the neural cell adhesion molecule L1. Faseb J., 37, 2023
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8DPU
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![BU of 8dpu by Molmil](/molmil-images/mine/8dpu) | The crystal structure of the IL-11 signalling complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... | Authors: | Metcalfe, R.D, Aizel, K, Griffin, M.D.W. | Deposit date: | 2022-07-17 | Release date: | 2023-11-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.78 Å) | Cite: | Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14, 2023
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8DPS
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![BU of 8dps by Molmil](/molmil-images/mine/8dps) | The structure of the interleukin 11 signalling complex, truncated gp130 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... | Authors: | Metcalfe, R.D, Hanssen, E, Griffin, M.D.W. | Deposit date: | 2022-07-17 | Release date: | 2023-11-29 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14, 2023
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8DPT
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![BU of 8dpt by Molmil](/molmil-images/mine/8dpt) | The structure of the IL-11 signalling complex, with full-length extracellular gp130 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... | Authors: | Metcalfe, R.D, Hanssen, E, Griffin, M.D.W. | Deposit date: | 2022-07-17 | Release date: | 2023-11-29 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14, 2023
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8DH8
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![BU of 8dh8 by Molmil](/molmil-images/mine/8dh8) | |
7Y8S
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![BU of 7y8s by Molmil](/molmil-images/mine/7y8s) | |
7Y8I
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![BU of 7y8i by Molmil](/molmil-images/mine/7y8i) | Crystal structure of sDscam FNIII3 domain, isoform alpha7 | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Dscam, ... | Authors: | Chen, Q, Yu, Y, Cheng, J. | Deposit date: | 2022-06-24 | Release date: | 2023-05-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for the self-recognition of sDSCAM in Chelicerata. Nat Commun, 14, 2023
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7Y8H
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![BU of 7y8h by Molmil](/molmil-images/mine/7y8h) | |
7Y6E
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![BU of 7y6e by Molmil](/molmil-images/mine/7y6e) | |
7Y5R
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![BU of 7y5r by Molmil](/molmil-images/mine/7y5r) | |
8D74
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![BU of 8d74 by Molmil](/molmil-images/mine/8d74) | |
8D7R
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![BU of 8d7r by Molmil](/molmil-images/mine/8d7r) | |
8D7E
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![BU of 8d7e by Molmil](/molmil-images/mine/8d7e) | |
8D7H
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![BU of 8d7h by Molmil](/molmil-images/mine/8d7h) | Cryo-EM structure of human CLCF1 in complex with CRLF1 and CNTFR alpha | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cardiotrophin-like cytokine factor 1, ... | Authors: | Zhou, Y, Franklin, M.C. | Deposit date: | 2022-06-07 | Release date: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into the assembly of gp130 family cytokine signaling complexes. Sci Adv, 9, 2023
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8D82
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![BU of 8d82 by Molmil](/molmil-images/mine/8d82) | |
8D85
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![BU of 8d85 by Molmil](/molmil-images/mine/8d85) | |
8D6A
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![BU of 8d6a by Molmil](/molmil-images/mine/8d6a) | |
8A16
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![BU of 8a16 by Molmil](/molmil-images/mine/8a16) | Human PTPRM domains FN3-4, in spacegroup P212121 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Caroe, E, Graham, S.C, Sharpe, H.J, Deane, J.E. | Deposit date: | 2022-05-31 | Release date: | 2023-03-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299, 2023
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8A17
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![BU of 8a17 by Molmil](/molmil-images/mine/8a17) | Human PTPRM domains FN3-4, in spacegroup P3221 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, ... | Authors: | Shamin, M, Graham, S.C, Sharpe, H.J, Deane, J.E. | Deposit date: | 2022-05-31 | Release date: | 2023-03-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299, 2023
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7ZXK
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![BU of 7zxk by Molmil](/molmil-images/mine/7zxk) | Human IL-27 in complex with neutralizing SRF388 FAb fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 subunit alpha, Interleukin-27 subunit beta, ... | Authors: | Bloch, Y, Skladanowska, K, Strand, J, Welin, M, Logan, D, Hill, J, Savvides, S.N. | Deposit date: | 2022-05-21 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27. Cell Rep, 41, 2022
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