8DTM

Cryo-EM structure of insulin receptor (IR) bound with S597 component 2

Summary for 8DTM

Entry DOI	10.2210/pdb8dtm/pdb
EMDB information	27704 27705
Descriptor	Insulin receptor, Insulin mimetic peptide S597 component 2 (2 entities in total)
Functional Keywords	signaling protein
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	3
Total formula weight	308751.63
Authors	Park, J.,Li, J.,Mayer, J.P.,Ball, K.A.,Wu, J.Y.,Hall, C.,Accili, D.,Stowell, M.H.B.,Bai, X.C.,Choi, E. (deposition date: 2022-07-26, release date: 2022-09-07, Last modification date: 2022-10-12)
Primary citation	Park, J.,Li, J.,Mayer, J.P.,Ball, K.A.,Wu, J.,Hall, C.,Accili, D.,Stowell, M.H.B.,Bai, X.C.,Choi, E. Activation of the insulin receptor by an insulin mimetic peptide. Nat Commun, 13:5594-5594, 2022 Cited by PubMed: 36151101 DOI: 10.1038/s41467-022-33274-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.5 Å)

Structure validation