7YQ6

human insulin receptor bound with A62 DNA aptamer

Summary for 7YQ6

• Entry DOI: 10.2210/pdb7yq6/pdb
• EMDB information: 34021
• Descriptor: Isoform Short of Insulin receptor, IR-A62 aptamer (2 entities in total)
• Functional Keywords: receptor-ligand complex_c, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 224300.75

Authors

Kim, J.,Yunn, N.,Ryu, S.,Cho, Y. (deposition date: 2022-08-05, release date: 2022-11-09, Last modification date: 2024-05-08)

• Primary citation: Kim, J.,Yunn, N.O.,Park, M.,Kim, J.,Park, S.,Kim, Y.,Noh, J.,Ryu, S.H.,Cho, Y.; Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures.; Nat Commun, 13:6500-6500, 2022; PubMed: 36310231; DOI: 10.1038/s41467-022-34292-8

Experimental method

ELECTRON MICROSCOPY (4.18 Å)