7YQ6
human insulin receptor bound with A62 DNA aptamer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (E, F) | Isoform Short of Insulin receptor | polymer | 907 | 103623.6 | 2 | UniProt (P06213) Pfam (PF01030) Pfam (PF00757) Pfam (PF00041) | Homo sapiens (human) | IR |
| 2 | C, D (G, H) | IR-A62 aptamer | polymer | 24 | 8526.8 | 2 | synthetic construct |
Sequence modifications
E, F: 1 - 907 (UniProt: P06213)
| PDB | External Database | Details |
|---|---|---|
| His 144 | Tyr 171 | conflict |
| Thr 421 | Ile 448 | conflict |
| Lys 465 | Gln 492 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 224300.8 | |
| All* | Total formula weight | 224300.8 |
