8DH8

Leptin-bound leptin receptor complex-full ECD

Summary for 8DH8

• Entry DOI: 10.2210/pdb8dh8/pdb
• EMDB information: 27432
• Descriptor: Leptin receptor, Leptin (2 entities in total)
• Functional Keywords: ob, receptor, cytokine, hormone, signaling protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 3
• Total formula weight: 210253.25

Authors

Saxton, R.A.,Caveney, N.A.,Garcia, K.C. (deposition date: 2022-06-25, release date: 2023-04-19, Last modification date: 2024-06-12)

• Primary citation: Saxton, R.A.,Caveney, N.A.,Moya-Garzon, M.D.,Householder, K.D.,Rodriguez, G.E.,Burdsall, K.A.,Long, J.Z.,Garcia, K.C.; Structural insights into the mechanism of leptin receptor activation.; Nat Commun, 14:1797-1797, 2023; PubMed: 37002197; DOI: 10.1038/s41467-023-37169-6

Experimental method

ELECTRON MICROSCOPY (5.9 Å)