8DTL
Cryo-EM structure of insulin receptor (IR) bound with S597 peptide
Summary for 8DTL
| Entry DOI | 10.2210/pdb8dtl/pdb |
| EMDB information | 27704 |
| Descriptor | Insulin mimetic peptide S597, Insulin receptor (2 entities in total) |
| Functional Keywords | insulin receptor, s597, signaling protein |
| Biological source | Mus musculus (house mouse) More |
| Total number of polymer chains | 4 |
| Total formula weight | 314043.31 |
| Authors | Park, J.,Li, J.,Mayer, J.P.,Ball, K.A.,Wu, J.Y.,Hall, C.,Accili, D.,Stowell, M.H.B.,Bai, X.C.,Choi, E. (deposition date: 2022-07-25, release date: 2022-09-07, Last modification date: 2022-10-12) |
| Primary citation | Park, J.,Li, J.,Mayer, J.P.,Ball, K.A.,Wu, J.,Hall, C.,Accili, D.,Stowell, M.H.B.,Bai, X.C.,Choi, E. Activation of the insulin receptor by an insulin mimetic peptide. Nat Commun, 13:5594-5594, 2022 Cited by PubMed: 36151101DOI: 10.1038/s41467-022-33274-0 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (5.4 Å) |
Structure validation
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