1I8G
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![BU of 1i8g by Molmil](/molmil-images/mine/1i8g) | SOLUTION STRUCTURE OF PIN1 WW DOMAIN COMPLEXED WITH CDC25 PHOSPHOTHREONINE PEPTIDE | Descriptor: | M-PHASE INDUCER PHOSPHATASE 3, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 | Authors: | Wintjens, R, Wieruszeski, J.-M, Drobecq, H, Lippens, G, Landrieu, I. | Deposit date: | 2001-03-14 | Release date: | 2001-07-18 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | 1H NMR study on the binding of Pin1 Trp-Trp domain with phosphothreonine peptides. J.Biol.Chem., 276, 2001
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1VWT
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![BU of 1vwt by Molmil](/molmil-images/mine/1vwt) | T STATE HUMAN HEMOGLOBIN [ALPHA V96W], ALPHA AQUOMET, BETA DEOXY | Descriptor: | HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Puius, Y.A, Zou, M, Ho, N.T, Ho, C, Almo, S.C. | Deposit date: | 1997-03-20 | Release date: | 1998-03-25 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Novel water-mediated hydrogen bonds as the structural basis for the low oxygen affinity of the blood substitute candidate rHb(alpha 96Val-->Trp). Biochemistry, 37, 1998
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1I6C
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![BU of 1i6c by Molmil](/molmil-images/mine/1i6c) | SOLUTION STRUCTURE OF PIN1 WW DOMAIN | Descriptor: | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 | Authors: | Wintjens, R, Wieruszeski, J.-M, Drobecq, H, Lippens, G, Landrieu, I. | Deposit date: | 2001-03-02 | Release date: | 2001-07-18 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | 1H NMR study on the binding of Pin1 Trp-Trp domain with phosphothreonine peptides. J.Biol.Chem., 276, 2001
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1I8H
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![BU of 1i8h by Molmil](/molmil-images/mine/1i8h) | SOLUTION STRUCTURE OF PIN1 WW DOMAIN COMPLEXED WITH HUMAN TAU PHOSPHOTHREONINE PEPTIDE | Descriptor: | MICROTUBULE-ASSOCIATED PROTEIN TAU, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 | Authors: | Wintjens, R, Wieruszeski, J.-M, Drobecq, H, Lippens, G, Landrieu, I. | Deposit date: | 2001-03-14 | Release date: | 2001-07-18 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | 1H NMR study on the binding of Pin1 Trp-Trp domain with phosphothreonine peptides. J.Biol.Chem., 276, 2001
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5HUE
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![BU of 5hue by Molmil](/molmil-images/mine/5hue) | DAHP synthase from Corynebacterium glutamicum in complex with tryptophan | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, ... | Authors: | Burschowsky, D, Heim, J.B, Thorbjoernsrud, H.V, Krengel, U. | Deposit date: | 2016-01-27 | Release date: | 2017-08-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp. Biochemistry, 57, 2018
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2JTZ
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![BU of 2jtz by Molmil](/molmil-images/mine/2jtz) | Solution structure and chemical shift assignments of the F104-to-5-flurotryptophan mutant of cardiac troponin C | Descriptor: | Troponin C, slow skeletal and cardiac muscles | Authors: | Wang, X, Mercier, P, Letourneau, P, Sykes, B.D. | Deposit date: | 2007-08-10 | Release date: | 2007-08-28 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies Protein Sci., 14, 2005
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2JT0
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![BU of 2jt0 by Molmil](/molmil-images/mine/2jt0) | Solution structure of F104W cardiac troponin C | Descriptor: | Troponin C, slow skeletal and cardiac muscles | Authors: | Wang, X, Mercier, P, Letourneau, P.-J, Sykes, B.D. | Deposit date: | 2007-07-17 | Release date: | 2008-05-27 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies. Protein Sci., 14, 2005
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5HUC
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![BU of 5huc by Molmil](/molmil-images/mine/5huc) | DAHP synthase from Corynebacterium glutamicum | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, MANGANESE (II) ION, ... | Authors: | Burschowsky, D, Heim, J.B, Thorbjoernsrud, H.V, Krengel, U. | Deposit date: | 2016-01-27 | Release date: | 2017-08-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp. Biochemistry, 57, 2018
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2JT8
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![BU of 2jt8 by Molmil](/molmil-images/mine/2jt8) | Solution structure of the F153-to-5-flurotryptophan mutant of human cardiac troponin C | Descriptor: | Troponin C, slow skeletal and cardiac muscles | Authors: | Wang, X, Mercier, P, Letourneau, P, Sykes, B.D. | Deposit date: | 2007-07-20 | Release date: | 2007-08-07 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies Protein Sci., 14, 2005
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6T9N
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![BU of 6t9n by Molmil](/molmil-images/mine/6t9n) | CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(4,5)P2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Wang, Q, Pike, A.C.W, Grieben, M, Baronina, A, Nasrallah, C, Shintre, C, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | Deposit date: | 2019-10-28 | Release date: | 2019-11-20 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2. Structure, 28, 2020
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6T9O
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![BU of 6t9o by Molmil](/molmil-images/mine/6t9o) | CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(3,5)P2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Wang, Q, Pike, A.C.W, Grieben, M, Baronina, A, Nasrallah, C, Shintre, C, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | Deposit date: | 2019-10-28 | Release date: | 2019-11-20 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2. Structure, 28, 2020
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6IQX
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![BU of 6iqx by Molmil](/molmil-images/mine/6iqx) | High resolution structure of bilirubin oxidase from Myrothecium verrucaria - M467Q mutant, aerobically prepared | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Bilirubin oxidase, ... | Authors: | Shibata, N, Akter, M, Higuchi, Y. | Deposit date: | 2018-11-09 | Release date: | 2018-11-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.432 Å) | Cite: | Redox Potential-Dependent Formation of an Unusual His-Trp Bond in Bilirubin Oxidase. Chemistry, 24, 2018
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1RVW
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![BU of 1rvw by Molmil](/molmil-images/mine/1rvw) | R STATE HUMAN HEMOGLOBIN [ALPHA V96W], CARBONMONOXY | Descriptor: | CARBON MONOXIDE, HEMOGLOBIN, PHOSPHATE ION, ... | Authors: | Puius, Y.A, Zou, M, Ho, N.T, Ho, C, Almo, S.C. | Deposit date: | 1997-03-20 | Release date: | 1998-03-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Novel water-mediated hydrogen bonds as the structural basis for the low oxygen affinity of the blood substitute candidate rHb(alpha 96Val-->Trp). Biochemistry, 37, 1998
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1GHD
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![BU of 1ghd by Molmil](/molmil-images/mine/1ghd) | Crystal structure of the glutaryl-7-aminocephalosporanic acid acylase by mad phasing | Descriptor: | GLUTARYL-7-AMINOCEPHALOSPORANIC ACID ACYLASE | Authors: | Ding, Y, Jiang, W, Mao, X, He, H, Zhang, S, Tang, H, Bartlam, M, Ye, S, Jiang, F, Liu, Y, Zhao, G, Rao, Z. | Deposit date: | 2000-12-07 | Release date: | 2003-07-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Affinity alkylation of the Trp-B4 residue of the beta -subunit of the glutaryl 7-aminocephalosporanic acid acylase of Pseudomonas sp. 130. J.Biol.Chem., 277, 2002
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1ZBC
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![BU of 1zbc by Molmil](/molmil-images/mine/1zbc) | Crystal Structure of the porcine signalling protein liganded with the peptide Trp-Pro-Trp (WPW) at 2.3 A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3 mer peptide, signal processing protein | Authors: | Srivastava, D.B, Kaur, P, Kumar, J, Somvanshi, R.K, Sharma, S, Dey, S, Singh, T.P. | Deposit date: | 2005-04-08 | Release date: | 2005-04-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Crystal Structure of the porcine signalling protein liganded with the peptide Trp-Pro-Trp (WPW) at 2.3 A resolution To be Published
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6CUZ
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![BU of 6cuz by Molmil](/molmil-images/mine/6cuz) | Engineered TrpB from Pyrococcus furiosus, PfTrpB7E6 with (2S,3R)-ethylserine bound as the amino-acrylate | Descriptor: | (2E)-2-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]pent-2-enoic acid, PHOSPHATE ION, SODIUM ION, ... | Authors: | Scheele, R.A, Buller, A.R, Boville, C.E, Arnold, F.H. | Deposit date: | 2018-03-27 | Release date: | 2018-09-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Engineered Biosynthesis of beta-Alkyl Tryptophan Analogues. Angew. Chem. Int. Ed. Engl., 57, 2018
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2OH9
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![BU of 2oh9 by Molmil](/molmil-images/mine/2oh9) | Myoglobin cavity mutant V68W | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Phillips Jr, G.N, Li, T, Brucker, E.A, Soman, J, Olson, J.S. | Deposit date: | 2007-01-09 | Release date: | 2007-01-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Ligand pathways in myoglobin: A review of trp cavity mutations. Iubmb Life, 59, 2007
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1PWU
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![BU of 1pwu by Molmil](/molmil-images/mine/1pwu) | Crystal Structure of Anthrax Lethal Factor complexed with (3-(N-hydroxycarboxamido)-2-isobutylpropanoyl-Trp-methylamide), a known small molecule inhibitor of matrix metalloproteases. | Descriptor: | 3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE, Lethal factor, ZINC ION | Authors: | Wong, T.Y, Schwarzenbacher, R, Liddington, R.C. | Deposit date: | 2003-07-02 | Release date: | 2004-02-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor. Nat.Struct.Mol.Biol., 11, 2004
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5HUB
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![BU of 5hub by Molmil](/molmil-images/mine/5hub) | High-resolution structure of chorismate mutase from Corynebacterium glutamicum | Descriptor: | Chorismate mutase, FORMIC ACID | Authors: | Burschowsky, D, Heim, J.B, Thorbjoernsrud, H.V, Krengel, U. | Deposit date: | 2016-01-27 | Release date: | 2017-08-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.06 Å) | Cite: | Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp. Biochemistry, 57, 2018
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7QRI
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![BU of 7qri by Molmil](/molmil-images/mine/7qri) | Regulatory domain dimer of tryptophan hydroxylase 2 in complex with L-Phe | Descriptor: | PHENYLALANINE, Tryptophan 5-hydroxylase 2 | Authors: | Vedel, I.M, Prestel, A, Harris, P, Peters, G.H.J, Kragelund, B.B. | Deposit date: | 2022-01-11 | Release date: | 2023-05-03 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structural characterization of human tryptophan hydroxylase 2 reveals that L-Phe is superior to L-Trp as the regulatory domain ligand. Structure, 31, 2023
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7RJ1
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![BU of 7rj1 by Molmil](/molmil-images/mine/7rj1) | Crystal structure of Aro7p chorismate mutase from Candida albicans, complex with L-Trp | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Chorismate mutase, ... | Authors: | Stogios, P.J, Evdokimova, E, Tan, K, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-07-20 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Crystal structure of Aro7p chorismate mutase from Candida albicans, complex with L-Trp To Be Published
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5VM5
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![BU of 5vm5 by Molmil](/molmil-images/mine/5vm5) | Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9, with Ser bound | Descriptor: | 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, SODIUM ION, Tryptophan synthase beta chain 1, ... | Authors: | Buller, A.R, van Roye, P. | Deposit date: | 2017-04-26 | Release date: | 2017-05-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble. J. Am. Chem. Soc., 140, 2018
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1J9N
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![BU of 1j9n by Molmil](/molmil-images/mine/1j9n) | Solution Structure of the Nucleopeptide [AC-LYS-TRP-LYS-HSE(p3*dGCATCG)-ALA]-[p5*dCGTAGC] | Descriptor: | 5'-D(*CP*GP*TP*AP*GP*C)-3', 5'-D(*GP*CP*TP*AP*CP*(PGN))-3', peptide ACE-LYS-TRP-LYS-HSE-ALA | Authors: | Gomez-Pinto, I, Marchan, V, Gago, F, Grandas, A, Gonzalez, C. | Deposit date: | 2001-05-28 | Release date: | 2003-01-21 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Solution structure and stability of tryptophan-containing nucleopeptide duplexes Chembiochem, 4, 2003
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6AMH
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![BU of 6amh by Molmil](/molmil-images/mine/6amh) | |
6AM7
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![BU of 6am7 by Molmil](/molmil-images/mine/6am7) | |