7YW3

Crystal structure of tRNA 2'-phosphotransferase from Homo sapiens

Summary for 7YW3

Entry DOI	10.2210/pdb7yw3/pdb
Descriptor	tRNA 2'-phosphotransferase 1, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	trna 2'-phosphotransferase, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	28483.34
Authors	Yang, X.Y.,Liu, X.H. (deposition date: 2022-08-21, release date: 2023-07-26, Last modification date: 2023-08-30)
Primary citation	Yang, X.,Wang, J.,Li, S.,Li, X.,Gong, J.,Yan, Z.,Zhou, H.,Wu, C.,Liu, X. Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation. Nucleic Acids Res., 51:7649-7665, 2023 Cited by PubMed: 37334830 DOI: 10.1093/nar/gkad525 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation