5WPQ

Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed I conformation at 3.64 Angstrom resolution

Summary for 5WPQ

• Entry DOI: 10.2210/pdb5wpq/pdb
• Related: 5WPO 5WPT 5WPV
• EMDB information: 8881 8882 8883
• Descriptor: Mucolipin-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION (3 entities in total)
• Functional Keywords: ion channel, membrane protein
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 4
• Total formula weight: 268347.84

Authors

Chen, Q.,She, J.,Guo, J.,Bai, X.,Jiang, Y. (deposition date: 2017-08-07, release date: 2017-10-18, Last modification date: 2023-04-05)

• Primary citation: Chen, Q.,She, J.,Zeng, W.,Guo, J.,Xu, H.,Bai, X.C.,Jiang, Y.; Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.; Nature, 550:415-418, 2017; PubMed: 29019981; DOI: 10.1038/nature24035

Experimental method

ELECTRON MICROSCOPY (3.64 Å)