7WDB

Human TRPC5 channel in complex with riluzole

This is a non-PDB format compatible entry.

Summary for 7WDB

• Entry DOI: 10.2210/pdb7wdb/pdb
• EMDB information: 32436
• Descriptor: Short transient receptor potential channel 5, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL HEMISUCCINATE, ... (8 entities in total)
• Functional Keywords: trpc5, riluzole, activator, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 366767.62

Authors

Chen, L.,Wei, M.,Yang, Y. (deposition date: 2021-12-21, release date: 2022-04-13, Last modification date: 2025-03-26)

• Primary citation: Yang, Y.,Wei, M.,Chen, L.; Structural identification of riluzole-binding site on human TRPC5.; Cell Discov, 8:67-67, 2022; PubMed: 35821012; DOI: 10.1038/s41421-022-00410-5

Experimental method

ELECTRON MICROSCOPY (2.4 Å)