7WDB
Human TRPC5 channel in complex with riluzole
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005216 | molecular_function | monoatomic ion channel activity |
A | 0005262 | molecular_function | calcium channel activity |
A | 0006811 | biological_process | monoatomic ion transport |
A | 0016020 | cellular_component | membrane |
A | 0055085 | biological_process | transmembrane transport |
A | 0070588 | biological_process | calcium ion transmembrane transport |
B | 0005216 | molecular_function | monoatomic ion channel activity |
B | 0005262 | molecular_function | calcium channel activity |
B | 0006811 | biological_process | monoatomic ion transport |
B | 0016020 | cellular_component | membrane |
B | 0055085 | biological_process | transmembrane transport |
B | 0070588 | biological_process | calcium ion transmembrane transport |
C | 0005216 | molecular_function | monoatomic ion channel activity |
C | 0005262 | molecular_function | calcium channel activity |
C | 0006811 | biological_process | monoatomic ion transport |
C | 0016020 | cellular_component | membrane |
C | 0055085 | biological_process | transmembrane transport |
C | 0070588 | biological_process | calcium ion transmembrane transport |
D | 0005216 | molecular_function | monoatomic ion channel activity |
D | 0005262 | molecular_function | calcium channel activity |
D | 0006811 | biological_process | monoatomic ion transport |
D | 0016020 | cellular_component | membrane |
D | 0055085 | biological_process | transmembrane transport |
D | 0070588 | biological_process | calcium ion transmembrane transport |
Functional Information from PROSITE/UniProt
site_id | PS00962 |
Number of Residues | 12 |
Details | RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. LiSLFTANSHLG |
Chain | Residue | Details |
A | LEU493-GLY504 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1464 |
Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
Chain | Residue | Details |
A | MET1-LYS330 | |
D | MET1-LYS330 | |
D | LYS420-LEU437 | |
D | ARG492-ARG512 | |
A | LYS420-LEU437 | |
A | ARG492-ARG512 | |
B | MET1-LYS330 | |
B | LYS420-LEU437 | |
B | ARG492-ARG512 | |
C | MET1-LYS330 | |
C | LYS420-LEU437 | |
C | ARG492-ARG512 |
site_id | SWS_FT_FI2 |
Number of Residues | 480 |
Details | TRANSMEM: Helical => ECO:0000255 |
Chain | Residue | Details |
A | LEU331-SER351 | |
B | MET471-LEU491 | |
B | MET513-ASN533 | |
B | MET604-MET624 | |
C | LEU331-SER351 | |
C | PRO399-ILE419 | |
C | MET438-VAL458 | |
C | MET471-LEU491 | |
C | MET513-ASN533 | |
C | MET604-MET624 | |
D | LEU331-SER351 | |
A | PRO399-ILE419 | |
D | PRO399-ILE419 | |
D | MET438-VAL458 | |
D | MET471-LEU491 | |
D | MET513-ASN533 | |
D | MET604-MET624 | |
A | MET438-VAL458 | |
A | MET471-LEU491 | |
A | MET513-ASN533 | |
A | MET604-MET624 | |
B | LEU331-SER351 | |
B | PRO399-ILE419 | |
B | MET438-VAL458 |
site_id | SWS_FT_FI3 |
Number of Residues | 504 |
Details | TOPO_DOM: Extracellular => ECO:0000255 |
Chain | Residue | Details |
A | PRO352-PRO398 | |
D | PRO352-PRO398 | |
D | LYS459-GLU470 | |
D | GLY534-THR603 | |
A | LYS459-GLU470 | |
A | GLY534-THR603 | |
B | PRO352-PRO398 | |
B | LYS459-GLU470 | |
B | GLY534-THR603 | |
C | PRO352-PRO398 | |
C | LYS459-GLU470 | |
C | GLY534-THR603 |
site_id | SWS_FT_FI4 |
Number of Residues | 4 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN461 | |
B | ASN461 | |
C | ASN461 | |
D | ASN461 |