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3KG5
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Crystal structure of human Ig-beta homodimer
Descriptor: B-cell antigen receptor complex-associated protein beta chain
Authors:Radaev, S, Sun, P.D.
Deposit date:2009-10-28
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and Functional Studies of Igalphabeta and Its Assembly with the B Cell Antigen Receptor.
Structure, 18, 2010
3KHO
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BU of 3kho by Molmil
Crystal structure of murine Ig-beta (CD79b) homodimer
Descriptor: B-cell antigen receptor complex-associated protein beta chain, SULFATE ION
Authors:Radaev, S, Sun, P.D.
Deposit date:2009-10-30
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Structural and Functional Studies of Igalphabeta and Its Assembly with the B Cell Antigen Receptor.
Structure, 18, 2010
3LVE
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BU of 3lve by Molmil
LEN Q38E MUTANT: A DOMAIN FLIP FROM A SINGLE AMINO ACID SUBSTITUTION
Descriptor: LEN, ZINC ION
Authors:Schiffer, M, Pokkuluri, P.R.
Deposit date:1998-05-12
Release date:1999-05-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:A domain flip as a result of a single amino-acid substitution.
Structure, 6, 1998
3M45
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BU of 3m45 by Molmil
Crystal structure of Ig1 domain of mouse SynCAM 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell adhesion molecule 2
Authors:Yue, L, Modis, Y.
Deposit date:2010-03-10
Release date:2010-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:N-glycosylation at the SynCAM (synaptic cell adhesion molecule) immunoglobulin interface modulates synaptic adhesion.
J.Biol.Chem., 285, 2010
3MCG
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BU of 3mcg by Molmil
THREE-DIMENSIONAL STRUCTURE OF A LIGHT CHAIN DIMER CRYSTALLIZED IN WATER. CONFORMATIONAL FLEXIBILITY OF A MOLECULE IN TWO CRYSTAL FORMS
Descriptor: IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN)
Authors:Ely, K.R, Herron, J.N, Edmundson, A.B.
Deposit date:1989-05-09
Release date:1990-10-15
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structure of a light chain dimer crystallized in water. Conformational flexibility of a molecule in two crystal forms.
J.Mol.Biol., 210, 1989
3MJ9
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BU of 3mj9 by Molmil
Crystal structure of JAML in complex with the stimulatory antibody HL4E10
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Junctional adhesion molecule-like, STIMULATORY HAMSTER ANTIBODY HL4E10 FAB HEAVY CHAIN, ...
Authors:Verdino, P, Wilson, I.A.
Deposit date:2010-04-12
Release date:2011-02-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Molecular insights into gamma delta T cell costimulation by an anti-JAML antibody.
Structure, 19, 2011
3J6L
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BU of 3j6l by Molmil
Kinetic and Structural Analysis of Coxsackievirus B3 Receptor Interactions and Formation of the A-particle
Descriptor: Coxsackievirus and adenovirus receptor, SULFATE ION
Authors:Organtini, L.J, Makhov, A.M, Conway, J.F, Hafenstein, S, Carson, S.D.
Deposit date:2014-03-19
Release date:2014-04-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Kinetic and structural analysis of coxsackievirus b3 receptor interactions and formation of the a-particle.
J.Virol., 88, 2014
3MJ6
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BU of 3mj6 by Molmil
Crystal structure of the gammadelta T cell costimulatory receptor Junctional Adhesion Molecule-Like Protein, JAML
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FORMIC ACID, Junctional adhesion molecule-like, ...
Authors:Verdino, P, Wilson, I.A.
Deposit date:2010-04-12
Release date:2010-09-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K.
Science, 329, 2010
3KAA
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BU of 3kaa by Molmil
Structure of Tim-3 in complex with phosphatidylserine
Descriptor: 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, CALCIUM ION, Hepatitis A virus cellular receptor 2
Authors:Ballesteros, A, Santiago, C, Casasnovas, J.M.
Deposit date:2009-10-19
Release date:2010-01-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells.
J.Immunol., 184, 2010
3J6M
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BU of 3j6m by Molmil
Kinetic and Structural Analysis of Coxsackievirus B3 Receptor Interactions and Formation of the A-particle
Descriptor: Coxsackievirus and adenovirus receptor
Authors:Organtini, L.J, Makhov, A.M, Conway, J.F, Hafenstein, S, Carson, S.D.
Deposit date:2014-03-19
Release date:2014-04-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Kinetic and structural analysis of coxsackievirus b3 receptor interactions and formation of the a-particle.
J.Virol., 88, 2014
4Y8A
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BU of 4y8a by Molmil
Crystal Structure of the N-terminal domain of CEACAM6
Descriptor: Carcinoembryonic antigen-related cell adhesion molecule 6, GLYCEROL, ZINC ION
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2015-02-16
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Diverse oligomeric states of CEACAM IgV domains.
Proc.Natl.Acad.Sci.USA, 112, 2015
4Y89
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Crystal structure of the N-terminal domain of CEACAM7
Descriptor: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 7
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2015-02-16
Release date:2015-09-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structure of the N-terminal dimerization domain of CEACAM7.
Acta Crystallogr.,Sect.F, 71, 2015
4YIQ
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BU of 4yiq by Molmil
Structure of the CEACAM6-CEACAM8 heterodimer
Descriptor: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 6, Carcinoembryonic antigen-related cell adhesion molecule 8, ...
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2015-03-02
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Diverse oligomeric states of CEACAM IgV domains.
Proc.Natl.Acad.Sci.USA, 112, 2015
4DFH
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BU of 4dfh by Molmil
Crystal structure of cell adhesion molecule nectin-2/CD112 variable domain
Descriptor: Poliovirus receptor-related protein 2
Authors:Liu, J, Qian, X, Chen, Z, Xu, X, Gao, F, Zhang, S, Zhang, R, Qi, J, Gao, G.F, Yan, J.
Deposit date:2012-01-23
Release date:2012-06-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226
J.Immunol., 188, 2012
4ZQK
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BU of 4zqk by Molmil
Structure of the complex of human programmed death-1 (PD-1) and its ligand PD-L1.
Descriptor: Programmed cell death 1 ligand 1, Programmed cell death protein 1, SODIUM ION
Authors:Zak, K.M, Dubin, G, Holak, T.A.
Deposit date:2015-05-10
Release date:2015-11-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1.
Structure, 23, 2015
5A2L
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BU of 5a2l by Molmil
Crystal structure of scFv-SM3 in complex with APD-CGalNAc-RP
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, MODIFIED ANTIGEN TN, ...
Authors:Martinez-Saez, N, Castro-Lopez, J, Valero-Gonzalez, J, Madariaga, D, Companon, I, Somovilla, V.J, Salvado, M, Asensio, J.L, Jimenez-Barbero, J, Avenoza, A, Busto, J.H, Bernardes, G.J.L, Peregrina, J.M, Hurtado-Guerrero, R, Corzana, F.
Deposit date:2015-05-20
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an Anti-Muc1 Antibody.
Angew.Chem.Int.Ed.Engl., 54, 2015
4GOS
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BU of 4gos by Molmil
Crystal structure of human B7-H4 IgV-like domain
Descriptor: V-set domain-containing T-cell activation inhibitor 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Vigdorovich, V, Ramagopal, U, Bhosle, R, Toro, R, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-08-20
Release date:2012-09-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structure and cancer immunotherapy of the B7 family member B7x.
Cell Rep, 9, 2014
4Y88
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BU of 4y88 by Molmil
Crystal structure of the N-terminal domain of CEACAM8
Descriptor: 1,3-PROPANDIOL, CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 8, ...
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2015-02-16
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Diverse oligomeric states of CEACAM IgV domains.
Proc.Natl.Acad.Sci.USA, 112, 2015
5A2K
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BU of 5a2k by Molmil
Crystal structure of scFv-SM3 in complex with APD-TGalNAc-RP
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, ANTIGEN TN, ...
Authors:Martinez-Saez, N, Castro-Lopez, J, Valero-Gonzalez, J, Madariaga, D, Companon, I, Somovilla, V.J, Salvado, M, Asensio, J.L, Jimenez-Barbero, J, Avenoza, A, Busto, J.H, Bernardes, G.J.L, Peregrina, J.M, Hurtado-Guerrero, R, Corzana, F.
Deposit date:2015-05-20
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an Anti-Muc1 Antibody.
Angew.Chem.Int.Ed.Engl., 54, 2015
4H5S
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BU of 4h5s by Molmil
Complex structure of Necl-2 and CRTAM
Descriptor: Cell adhesion molecule 1, Cytotoxic and regulatory T-cell molecule
Authors:Zhang, S, Lu, G, Qi, J, Li, Y, Zhang, Z, Zhang, B, Yan, J, Gao, G.F.
Deposit date:2012-09-18
Release date:2013-08-07
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Competition of cell adhesion and immune recognition: insights into the interaction between CRTAM and nectin-like 2.
Structure, 21, 2013
5ACM
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BU of 5acm by Molmil
Mcg immunoglobulin variable domain with methylene blue
Descriptor: 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM, GLYCEROL, MCG, ...
Authors:Brumshtein, B, Esswein, S.R, Salwinski, L, Phillips, M.L, Ly, A.T, Cascio, D, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2015-08-17
Release date:2015-12-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain.
Elife, 4, 2015
5A2I
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BU of 5a2i by Molmil
Crystal structure of scFv-SM3 in complex with APD-SGalNAc-RP
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, ANTIGEN TN, ...
Authors:Martinez-Saez, N, Castro-Lopez, J, Valero-Gonzalez, J, Madariaga, D, Companon, I, Somovilla, V.J, Salvado, M, Asensio, J.L, Jimenez-Barbero, J, Avenoza, A, Busto, J.H, Bernardes, G.J.L, Peregrina, J.M, Hurtado-Guerrero, R, Corzana, F.
Deposit date:2015-05-20
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an Anti-Muc1 Antibody.
Angew.Chem.Int.Ed.Engl., 54, 2015
5WT9
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BU of 5wt9 by Molmil
Complex structure of PD-1 and nivolumab-Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Nivolumab, Light Chain of Nivolumab, ...
Authors:Tan, S, Zhang, H, Chai, Y, Song, H, Tong, Z, Wang, Q, Qi, J, Wong, G, Zhu, X, Liu, W.J, Gao, S, Wang, Z, Shi, Y, Yang, F, Gao, G.F, Yan, J.
Deposit date:2016-12-10
Release date:2017-02-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:An unexpected N-terminal loop in PD-1 dominates binding by nivolumab.
Nat Commun, 8, 2017
5X8M
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BU of 5x8m by Molmil
PD-L1 in complex with durvalumab
Descriptor: Programmed cell death 1 ligand 1, durvalumab heavy chain, durvalumab light chain
Authors:Heo, Y.S, Lee, H.T.
Deposit date:2017-03-03
Release date:2017-08-16
Method:X-RAY DIFFRACTION (2.661 Å)
Cite:Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab
Sci Rep, 7, 2017
5X8L
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BU of 5x8l by Molmil
PD-L1 in complex with atezolizumab
Descriptor: Programmed cell death 1 ligand 1, atezolizumab heavy chain, atezolizumab light chain
Authors:Heo, Y.S, Lee, H.T.
Deposit date:2017-03-03
Release date:2017-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab
Sci Rep, 7, 2017

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数据于2024-09-11公开中

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