PDB: 223790 resultsInfo pagesStatus searchChemie searchBIRD

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8Z8N	Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 3 Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*AP*GP*GP*CP*AP*GP*UP*U)-3'), ... Authors: Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. Deposit date: 2024-04-22 Release date: 2024-05-29 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.79 Å) Cite: Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024
9BJU	Crystal structure of the complex between VHL, ElonginB, ElonginC, and compound 5 Descriptor: 1,2-ETHANEDIOL, 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, ACETATE ION, ... Authors: Murray, J.M, Wu, H, Fuhrmann, J, Fairbrother, W.J, DiPasquale, A. Deposit date: 2024-04-25 Release date: 2024-05-29 Method: X-RAY DIFFRACTION (2.47 Å) Cite: Potency-enhanced peptidomimetic VHL ligands with improved oral bioavailability To Be Published
8XAY	Cryo-EM structure of an anti-phage defense complex bound to ATPrS and DNA Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding protein, DUF4297, ... Authors: An, Q, Deng, Z. Deposit date: 2023-12-05 Release date: 2024-06-05 Last modified: 2024-08-14 Method: ELECTRON MICROSCOPY (2.81 Å) Cite: Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex. Cell Res., 34, 2024
8XP8	Crystal structure of d(ACGmCCGT/ACGGCGT) in complex with Echinomycin Descriptor: 2-CARBOXYQUINOXALINE, DNA (5'-D(P*AP*CP*GP*(5CM)P*CP*GP*T)-3'), DNA (5'-D(P*AP*CP*GP*GP*CP*GP*T)-3'), ... Authors: Hou, M.H, Lin, S.M, Neidle, H. Deposit date: 2024-01-03 Release date: 2024-05-29 Last modified: 2024-08-14 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Structural basis of water-mediated cis Watson-Crick/Hoogsteen base-pair formation in non-CpG methylation. Nucleic Acids Res., 2024
3LWW	Structure of an open and closed conformation of Human Importin Beta bound to the Snurportin1 IBB-domain trapped in the same crystallographic asymmetric unit Descriptor: Importin subunit beta-1, Snurportin-1 Authors: Bhardwaj, A, Cingolani, G. Deposit date: 2010-02-24 Release date: 2010-06-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Conformational selection in the recognition of the snurportin importin beta binding domain by importin beta. Biochemistry, 49, 2010
8X8N	Cryo-EM structure of the octreotide-bound Somatostatin receptor 5-Gi protein complex Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha, ... Authors: Xu, H.E, You, C, Zhao, L, Li, J. Deposit date: 2023-11-27 Release date: 2024-06-12 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Cryo-EM structure of the octreotide-bound Somatostatin receptor 5-Gi protein complex To Be Published
8Z97	Cryo-EM structure of Thogoto virus polymerase in a transcription elongation conformation Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. Deposit date: 2024-04-22 Release date: 2024-05-29 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.65 Å) Cite: Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024
8YGJ	SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 28-nt) Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (51-MER), ... Authors: Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. Deposit date: 2024-02-26 Release date: 2024-06-05 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 631, 2024
3LXK	Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6 Descriptor: 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile, Tyrosine-protein kinase JAK3 Authors: Chrencik, J.E, Patny, A, Leung, I.K, Korniski, B, Emmons, T.L, Benson, T.E. Deposit date: 2010-02-25 Release date: 2010-06-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6. J.Mol.Biol., 400, 2010
8XOB	VMAT2 protonated state Descriptor: Synaptic vesicular amine transporter,transporter B Authors: Jiang, D.H, Wu, D. Deposit date: 2023-12-31 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.15 Å) Cite: VMAT2 protonated state To Be Published
8YX1	CD40 in complex with Bleselumab Fab Descriptor: Bleselumab, heavy chain, light chain, ... Authors: Caaveiro, J.M.M, Fernandez-Perez, J, Tsumoto, K. Deposit date: 2024-04-01 Release date: 2024-05-08 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structures of human CD40 in complex with monoclonal antibodies dacetuzumab and bleselumab. Biochem.Biophys.Res.Commun., 714, 2024
3LL3	The crystal structure of ligand bound xylulose kinase from Lactobacillus acidophilus Descriptor: 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Zhang, Z, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2010-01-28 Release date: 2010-03-23 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.002 Å) Cite: The crystal structure of xylulose kinase from Lactobacillus acidophilus To be Published
8XF0	Crystal structure of the dissociated C-phycocyanin alpha-chain from Thermoleptolyngbya sp. O-77 Descriptor: C-phycocyanin alpha chain, MAGNESIUM ION, PHYCOCYANOBILIN Authors: Nguyen, H.K, Teramoto, T, Kakuta, Y, Yoon, K.S. Deposit date: 2023-12-13 Release date: 2024-05-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Disassembly and reassembly of the non-conventional thermophilic C-phycocyanin. J.Biosci.Bioeng., 137, 2024
9B5X	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 10 map and model from cluster 5 (ATP/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Last modified: 2024-08-14 Method: ELECTRON MICROSCOPY (4.16 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway Nature, 2024
6DHS	Structure of hnRNP H qRRM1,2 Descriptor: Heterogeneous nuclear ribonucleoprotein H Authors: Meagher, J.L, Stuckey, J.A. Deposit date: 2018-05-21 Release date: 2018-09-12 Last modified: 2019-12-18 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Differential Conformational Dynamics Encoded by the Inter-qRRM linker of hnRNP H. J. Am. Chem. Soc., 2018
8YUV	Cryo-EM structure of the immepip-bound H3R-Gi complex Descriptor: 4-(1H-imidazol-5-ylmethyl)piperidine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y. Deposit date: 2024-03-27 Release date: 2024-06-05 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3 Å) Cite: Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs. Adv Sci, 11, 2024
8Z8J	Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 2 Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*AP*GP*GP*CP*AP*GP*UP*U)-3'), ... Authors: Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. Deposit date: 2024-04-22 Release date: 2024-05-29 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024
6QL6	Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ... Authors: Singh, K, Graf, B, Linden, A, Sautner, V, Urlaub, H, Tittmann, K, Stark, H, Chari, A. Deposit date: 2019-01-31 Release date: 2020-03-18 Last modified: 2020-04-08 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase. Cell, 180, 2020
8Z85	Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 1 Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*AP*GP*GP*CP*AP*GP*UP*U)-3'), ... Authors: Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. Deposit date: 2024-04-21 Release date: 2024-05-29 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024
8YR3	Cryo-EM structure of the human ABCB6 in complex with Cd(II):GSH Descriptor: ATP-binding cassette sub-family B member 6, CADMIUM ION, GLUTATHIONE Authors: Choi, S.H, Lee, S.S, Lee, H.Y, Kim, S, Kim, J.W, Jin, M.S. Deposit date: 2024-03-20 Release date: 2024-06-19 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Cryo-EM structure of cadmium-bound human ABCB6. Commun Biol, 7, 2024
8YKW	Cryo-EM structure of succinate receptor SUCR1 bound to succinic acid Descriptor: Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Li, C, Liu, H, Li, J, Zhu, H, Fu, W, Xu, H.E. Deposit date: 2024-03-05 Release date: 2024-05-29 Last modified: 2024-08-14 Method: ELECTRON MICROSCOPY (2.75 Å) Cite: Molecular basis of ligand recognition and activation of the human succinate receptor SUCR1. Cell Res., 34, 2024
3LP8	Crystal structure of phosphoribosylamine-glycine ligase from Ehrlichia chaffeensis Descriptor: PHOSPHATE ION, Phosphoribosylamine-glycine ligase, UNKNOWN ATOM OR ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-02-04 Release date: 2010-02-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal structure of phosphoribosylamine-glycine ligase from Ehrlichia chaffeensis To be Published
8ZMS	Acetylcholine-bound VAChT Descriptor: ACETYLCHOLINE, Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7 Authors: Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H. Deposit date: 2024-05-23 Release date: 2024-06-19 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural insights into VAChT neurotransmitter recognition and inhibition. Cell Res., 2024
3LNC	Crystal structure of guanylate kinase from Anaplasma phagocytophilum Descriptor: GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2010-02-02 Release date: 2010-02-16 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of guanylate kinase from Anaplasma phagocytophilum TO BE PUBLISHED
9BFL	Solution structure of the scorpion toxin omega-Buthitoxin-Hf1a Descriptor: Buthitoxin-Hf1a Authors: Rosengren, K.J, Payne, C.D. Deposit date: 2024-04-18 Release date: 2024-06-05 Method: SOLUTION NMR Cite: Novel Scorpion Toxin omega-Buthitoxin-Hf1a Selectively Inhibits Calcium Influx via Ca V 3.3 and Ca V 3.2 and Alleviates Allodynia in a Mouse Model of Acute Postsurgical Pain. Int J Mol Sci, 25, 2024

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