8YR3

Cryo-EM structure of the human ABCB6 in complex with Cd(II):GSH

Summary for 8YR3

Entry DOI	10.2210/pdb8yr3/pdb
Related	7DNZ 8K7C
EMDB information	39534
Descriptor	ATP-binding cassette sub-family B member 6, GLUTATHIONE, CADMIUM ION (3 entities in total)
Functional Keywords	cryo-em, abc transporter, atp-binding cassette transporter b6, abcb6, heme biosynthesis, heavy metal detoxification, glutathione, phytochelatin, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	144165.14
Authors	Choi, S.H.,Lee, S.S.,Lee, H.Y.,Kim, S.,Kim, J.W.,Jin, M.S. (deposition date: 2024-03-20, release date: 2024-06-19)
Primary citation	Choi, S.H.,Lee, S.S.,Lee, H.Y.,Kim, S.,Kim, J.W.,Jin, M.S. Cryo-EM structure of cadmium-bound human ABCB6. Commun Biol, 7:672-672, 2024 Cited by PubMed: 38822018 DOI: 10.1038/s42003-024-06377-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation