7DNZ

Cryo-EM structure of the human ABCB6 (Hemin and GSH-bound)

Summary for 7DNZ

Entry DOI	10.2210/pdb7dnz/pdb
EMDB information	30791
Descriptor	ATP-binding cassette sub-family B member 6, mitochondrial, GLUTATHIONE, CHOLESTEROL HEMISUCCINATE, ... (4 entities in total)
Functional Keywords	abcb6, heme transporter, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	192714.48
Authors	Kim, S.,Lee, S.S.,Park, J.G.,Kim, J.W.,Kim, S.,Kim, N.J.,Hong, S.,Kang, J.Y.,Jin, M.S. (deposition date: 2020-12-11, release date: 2022-06-22, Last modification date: 2022-08-31)
Primary citation	Kim, S.,Lee, S.S.,Park, J.G.,Kim, J.W.,Ju, S.,Choi, S.H.,Kim, S.,Kim, N.J.,Hong, S.,Kang, J.Y.,Jin, M.S. Structural Insights into Porphyrin Recognition by the Human ATP-Binding Cassette Transporter ABCB6. Mol.Cells, 45:575-587, 2022 Cited by PubMed: 35950458 DOI: 10.14348/molcells.2022.0040 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation