7DNZ

Cryo-EM structure of the human ABCB6 (Hemin and GSH-bound)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ATP-binding cassette sub-family B member 6, mitochondrial	polymer	842	93974.2	2	UniProt (Q9NP58) Pfam (PF16185) Pfam (PF00664) Pfam (PF00005)	Homo sapiens (human)	Mitochondrial ABC transporter 3,Mt-ABC transporter 3,P-glycoprotein-related protein,Ubiquitously-expressed mammalian ABC half transporter
2	C, D, I, J (A, B)	GLUTATHIONE	non-polymer		307.3	4	Chemie (GSH) PubChem (745) PubChem (54289881) PubChem (59012062) PubChem (124886) PubChem (445616) PubChem (448041) PubChem (9839547) PubChem (10924820) PubChem (15559593)
3	E, F, G, K, L... (A, B)	CHOLESTEROL HEMISUCCINATE	non-polymer		486.7	6	Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (57163942) PubChem (45489984) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (155804219) PubChem (169132514) PubChem (60078761) PubChem (73440805) PubChem (99567469) PubChem (65082) PubChem (124301053) PubChem (124302591) PubChem (363416) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (500055) PubChem (124914595) PubChem (124914596) PubChem (13301926) PubChem (13301927) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028)
4	H (B)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	1	Chemie (HEM)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	187948.3
Non-Polymers*	Number of molecules	11
	Total formula weight	4766.1
All*	Total formula weight	192714.5

*Water molecules are not included.