8YKW

Cryo-EM structure of succinate receptor SUCR1 bound to succinic acid

Summary for 8YKW

• Entry DOI: 10.2210/pdb8ykw/pdb
• EMDB information: 39374
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Antibody fragment ScFv16, ... (6 entities in total)
• Functional Keywords: succinate receptor, gpr91, cryo-em, sucr1, membrane protein, membrane protein-immune system complex, membrane protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 150849.18

Authors

Li, C.,Liu, H.,Li, J.,Zhu, H.,Fu, W.,Xu, H.E. (deposition date: 2024-03-05, release date: 2024-05-29, Last modification date: 2024-07-03)

• Primary citation: Li, C.,Liu, H.,Li, J.,He, X.,Zhu, H.,Fu, W.,Xu, H.E.; Molecular basis of ligand recognition and activation of the human succinate receptor SUCR1.; Cell Res., 2024; PubMed: 38834763; DOI: 10.1038/s41422-024-00984-7

Experimental method

ELECTRON MICROSCOPY (2.75 Å)