9BJU

Crystal structure of the complex between VHL, ElonginB, ElonginC, and compound 5

This is a non-PDB format compatible entry.

Summary for 9BJU

• Entry DOI: 10.2210/pdb9bju/pdb
• Descriptor: Elongin-B, DIMETHYL SULFOXIDE, Elongin-C, ... (11 entities in total)
• Functional Keywords: vhl, degradation, degrader, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 16
• Total formula weight: 175292.65

Authors

Murray, J.M.,Wu, H.,Fuhrmann, J.,Fairbrother, W.J.,DiPasquale, A. (deposition date: 2024-04-25, release date: 2024-05-29)

• Primary citation: Wu, H.,Murray, J.M.,Ishisoko, N.,Frommlet, A.,Fairbrother, W.J.,Fuhrmann, J.; Potency-enhanced peptidomimetic VHL ligands with improved oral bioavailability; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.47 Å)