6QL6

Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom

This is a large structure.

Summary for 6QL6

EMDB information4578
DescriptorFatty acid synthase subunit alpha, Fatty acid synthase subunit beta, [(3~{R})-4-azanyl-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] dihydrogen phosphate, ... (4 entities in total)
Functional Keywordsfatty acid synthase, acyl carrier protein, ketosynthase, ketoreductase, enoyl reductase, dehydratase, malonyl/palmitoyl transferase, acetyl transferase, phosphopantetheine transferase, transferase
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains12
Total molecular weight2613918.35
Authors
Singh, K.,Graf, B.,Linden, A.,Sautner, V.,Urlaub, H.,Tittmann, K.,Stark, H.,Chari, A. (deposition date: 2019-01-31, release date: 2020-03-18, Last modification date: 2020-03-25)
Primary citation
Singh, K.,Graf, B.,Linden, A.,Sautner, V.,Urlaub, H.,Tittmann, K.,Stark, H.,Chari, A.
Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Cell, 2020
PubMed: 32160528 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2020.02.034
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers3 1.1% 6.6%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
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