8YX1
CD40 in complex with Bleselumab Fab
Summary for 8YX1
Entry DOI | 10.2210/pdb8yx1/pdb |
Descriptor | Bleselumab, heavy chain, Bleselumab, light chain, Tumor necrosis factor receptor superfamily member 5, ... (4 entities in total) |
Functional Keywords | cd40, dacetuzumab, bleselumab, agonist activity, tumor necrosis factor, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 134944.52 |
Authors | Caaveiro, J.M.M.,Fernandez-Perez, J.,Tsumoto, K. (deposition date: 2024-04-01, release date: 2024-05-08) |
Primary citation | Asano, R.,Nakakido, M.,Fernandez-Perez, J.,Caaveiro, J.M.M.,Nagata, S.,Tsumoto, K. Crystal structures of Human CD40 in complex with monoclonal antibodies, Dacetuzumab and Bleselumab To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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