8YX1

CD40 in complex with Bleselumab Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (H, A)	Bleselumab, heavy chain	polymer	229	24351.4	2		Homo sapiens
2	B, E (L, B)	Bleselumab, light chain	polymer	213	23104.6	2		Homo sapiens
3	C, F (R, C)	Tumor necrosis factor receptor superfamily member 5	polymer	179	20016.3	2	UniProt (P25942) Pfam (PF00020)	Homo sapiens (human)	B-cell surface antigen CD40,Bp50,CD40L receptor,CDw40
4	G, H, I, J, K... (H, L, R, A, B...)	water	water		18.0	25	Chemie (HOH)

Sequence modifications

R, C: 1 - 173 (UniProt: P25942)

PDB	External Database	Details
His 174	-	expression tag
His 175	-	expression tag
His 176	-	expression tag
His 177	-	expression tag
His 178	-	expression tag
His 179	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	134944.5
All*	Total formula weight	134944.5

*Water molecules are not included.