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7FCP
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BU of 7fcp by Molmil
Crystallographic structure of two neutralizing antibodies in complex with SARS-CoV-2 spike receptor-binding Domain (RBD)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Zheng, P, Jin, T.
Deposit date:2021-07-15
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ultrapotent neutralizing antibodies against SARS-CoV-2 with a high degree of mutation resistance.
J.Clin.Invest., 132, 2022
7FAH
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BU of 7fah by Molmil
Immune complex of head region of CA09 HA and neutralizing antibody 12H5
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Li, T.T, Xue, W.H, Gu, Y, Li, S.W.
Deposit date:2021-07-06
Release date:2022-07-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.151 Å)
Cite:Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses.
Nat Commun, 13, 2022
4Z0B
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BU of 4z0b by Molmil
Crystal Structure of the Fab Fragment of Anti-ofloxacin Antibody and Exploration Its Receptor Binding Site
Descriptor: PHOSPHATE ION, antibody heavy chain, antibody light chain
Authors:He, K, Du, X, Sheng, W, Zhou, X, Wang, J, Wang, S.
Deposit date:2015-03-26
Release date:2016-04-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal Structure of the Fab Fragment of an Anti-ofloxacin Antibody and Exploration of Its Specific Binding.
J.Agric.Food Chem., 64, 2016
1DSF
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BU of 1dsf by Molmil
THE CRYSTAL STRUCTURE OF THE DISULFIDE-STABILIZED FV FRAGMENT OF ANTICANCER ANTIBODY B1: CONFORMATIONAL INFLUENCE OF AN ENGINEERED DISULFIDE BOND
Descriptor: ANTICANCER ANTIBODY B1
Authors:Almog, O, Gilliland, G.L.
Deposit date:1997-05-04
Release date:1998-05-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the disulfide-stabilized Fv fragment of anticancer antibody B1: conformational influence of an engineered disulfide bond.
Proteins, 31, 1998
6OZ4
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BU of 6oz4 by Molmil
Crystal structure of broadly neutralizing antibody N49P6 Fab in complex with HIV-1 BG505 SOSIP.664 Env trimer ectodomain.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Tolbert, W.D, Pazgier, M.
Deposit date:2019-05-15
Release date:2020-08-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.05 Å)
Cite:Near-Pan-neutralizing, Plasma Deconvoluted Antibody N49P6 Mimics Host Receptor CD4 in Its Quaternary Interactions with the HIV-1 Envelope Trimer.
Mbio, 2021
7CR5
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BU of 7cr5 by Molmil
Complex structure of a human monoclonal antibody with SARS-CoV-2 nucleocapsid protein NTD
Descriptor: Nucleoprotein, ZINC ION, monoclonal antibody chain H, ...
Authors:Chen, S, Kang, S.
Deposit date:2020-08-12
Release date:2021-03-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:A SARS-CoV-2 antibody curbs viral nucleocapsid protein-induced complement hyperactivation.
Nat Commun, 12, 2021
7CHO
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BU of 7cho by Molmil
Crystal structure of SARS-CoV-2 antibody P5A-1D2 with RBD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P5A-1D2 heavy chain, ...
Authors:Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q.
Deposit date:2020-07-06
Release date:2021-05-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.561 Å)
Cite:Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2.
Nat Commun, 12, 2021
7CHS
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BU of 7chs by Molmil
Crystal structure of SARS-CoV-2 antibody P22A-1D1 with RBD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P22A-1D1 heavy chain, ...
Authors:Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q.
Deposit date:2020-07-06
Release date:2021-05-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2.
Nat Commun, 12, 2021
7CHP
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BU of 7chp by Molmil
Crystal structure of SARS-CoV-2 antibody P5A-3C8 with RBD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P5A-3C8 heavy chain, ...
Authors:Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q.
Deposit date:2020-07-06
Release date:2021-05-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.357 Å)
Cite:Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2.
Nat Commun, 12, 2021
3H42
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BU of 3h42 by Molmil
Crystal structure of PCSK9 in complex with Fab from LDLR competitive antibody
Descriptor: Fab from LDLR competitive antibody: Heavy chain, Fab from LDLR competitive antibody: Light chain, Proprotein convertase subtilisin/kexin type 9, ...
Authors:Piper, D.E, Walker, N.P.C, Romanow, W.G, Thibault, S.T, Tsai, M.M, Yang, E.
Deposit date:2009-04-17
Release date:2009-05-05
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:From the Cover: A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Proc.Natl.Acad.Sci.USA, 106, 2009
1FH5
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BU of 1fh5 by Molmil
CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF THE MONOCLONAL ANTIBODY MAK33
Descriptor: MONOCLONAL ANTIBODY MAK33
Authors:Augustine, J.G, de la Calle, A, Knarr, G, Buchner, J, Frederick, C.A.
Deposit date:2000-07-31
Release date:2000-09-13
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of the fab fragment of the monoclonal antibody MAK33. Implications for folding and interaction with the chaperone bip.
J.Biol.Chem., 276, 2001
4K3E
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BU of 4k3e by Molmil
Crystal structure of bovine antibody BLV5B8 with ultralong CDR H3
Descriptor: BOVINE ANTIBODY WITH ULTRALONG CDR H3, HEAVY CHAIN, LIGHT CHAIN, ...
Authors:Ekiert, D.C, Wang, F, Wilson, I.A.
Deposit date:2013-04-10
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Reshaping antibody diversity.
Cell(Cambridge,Mass.), 153, 2013
3TPK
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BU of 3tpk by Molmil
Crystal structure of the oligomer-specific KW1 antibody fragment
Descriptor: 1,2-ETHANEDIOL, BENZAMIDINE, Immunoglobulin heavy chain antibody variable domain KW1
Authors:Parthier, C, Morgado, I, Stubbs, M.T, Fandrich, M.
Deposit date:2011-09-08
Release date:2012-07-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Molecular basis of beta-amyloid oligomer recognition with a conformational antibody fragment.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GXU
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BU of 4gxu by Molmil
Crystal structure of antibody 1F1 bound to the 1918 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 1F1, heavy chain, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2012-09-04
Release date:2012-12-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.294 Å)
Cite:Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses.
Plos Pathog., 8, 2012
4YK4
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BU of 4yk4 by Molmil
Human antibody 641 I-9 in complex with influenza hemagglutinin H1 Solomon Islands/03/2006
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 641 I-9 VHCH antibody, 641 I-9 VLCL antibody, ...
Authors:Schmidt, A.G, Harrison, S.C.
Deposit date:2015-03-03
Release date:2015-05-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Viral receptor-binding site antibodies with diverse germline origins.
Cell, 161, 2015
7CHY
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BU of 7chy by Molmil
Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26
Descriptor: Interleukin-1 beta, heavy chain of antibody binding fragment of IgG26, light chain of antibody binding fragment of IgG26
Authors:Lee, C.C, Wang, A.H.J, Kuo, W.C.
Deposit date:2020-07-06
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP.
J.Mol.Biol., 433, 2020
7CHZ
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BU of 7chz by Molmil
Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26A
Descriptor: Interleukin-1 beta, heavy chain of antibody binding fragment of IgG26A, light chain of antibody binding fragment of IgG26A
Authors:Lee, C.C, Wang, A.H.J, Kuo, W.C.
Deposit date:2020-07-06
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP.
J.Mol.Biol., 433, 2020
4QT5
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BU of 4qt5 by Molmil
Crystal Structure of 3BD10: A Monoclonal Antibody against the TSH Receptor
Descriptor: 3BD10 mouse monoclonal antibody, heavy chain, light chain
Authors:Hubbard, P.A, Chen, C.R, McLachlan, S.M, Rapoport, B, Murali, R.
Deposit date:2014-07-07
Release date:2015-04-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a TSH receptor monoclonal antibody: insight into Graves' disease pathogenesis.
Mol.Endocrinol., 29, 2015
1QOK
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BU of 1qok by Molmil
MFE-23 AN ANTI-CARCINOEMBRYONIC ANTIGEN SINGLE-CHAIN FV ANTIBODY
Descriptor: MFE-23 RECOMBINANT ANTIBODY FRAGMENT
Authors:Boehm, M.K, Corper, A.L, Wan, T, Sohi, M.K, Sutton, B.J, Thornton, J.D, Keep, P.A, Chester, K.A, Begent, R.H.J, Perkins, S.J.
Deposit date:1999-11-11
Release date:2000-11-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the Anti-Carcinoembryonic Antigen Single-Chain Fv Antibody Mfe-23 and a Model for Antigen Binding Based on Intermolecular Contacts
Biochem.J., 346, 2000
6MID
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BU of 6mid by Molmil
Cryo-EM structure of the ZIKV virion in complex with Fab fragments of the potently neutralizing human monoclonal antibody ZIKV-195
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein, ...
Authors:Long, F, Rossmann, M.G.
Deposit date:2018-09-19
Release date:2019-01-16
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
4K3D
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BU of 4k3d by Molmil
Crystal structure of bovine antibody BLV1H12 with ultralong CDR H3
Descriptor: BOVINE ANTIBODY WITH ULTRALONG CDR H3, HEAVY CHAIN, LIGHT CHAIN, ...
Authors:Ekiert, D.C, Wang, F, Wilson, I.A.
Deposit date:2013-04-10
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Reshaping antibody diversity.
Cell(Cambridge,Mass.), 153, 2013
2BFV
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BU of 2bfv by Molmil
MONOCLONAL ANTIBODY FRAGMENT FV4155 FROM E. COLI
Descriptor: ESTRIOL 3-(B-D-GLUCURONIDE), FV4155
Authors:Trinh, C.H, Phillips, S.E.V.
Deposit date:1997-05-27
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Antibody fragment Fv4155 bound to two closely related steroid hormones: the structural basis of fine specificity.
Structure, 5, 1997
1RZK
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BU of 1rzk by Molmil
HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ...
Authors:Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
3H3B
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BU of 3h3b by Molmil
Crystal structure of the single-chain Fv (scFv) fragment of an anti-ErbB2 antibody chA21 in complex with residues 1-192 of ErbB2 extracellular domain
Descriptor: Receptor tyrosine-protein kinase erbB-2, anti-ErbB2 antibody chA21
Authors:Zhou, H, Liu, Y, Niu, L, Zhu, J, Teng, M.
Deposit date:2009-04-16
Release date:2010-04-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural Insights into the Down-regulation of Overexpressed p185her2/neu Protein of Transformed Cells by the Antibody chA21.
J.Biol.Chem., 286, 2011
5EOR
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BU of 5eor by Molmil
Structure of the murine antibody Fab 8E3 bound to the vaccinia virus A27 peptide 101-110
Descriptor: Protein A27, SODIUM ION, anti vaccinia virus A27 antibody 8E3 heavy chain, ...
Authors:Matho, M.H, Zajonc, D.M.
Deposit date:2015-11-10
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox.
J.Virol., 90, 2016

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数据于2024-08-28公开中

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