6OZ4

Crystal structure of broadly neutralizing antibody N49P6 Fab in complex with HIV-1 BG505 SOSIP.664 Env trimer ectodomain.

Summary for 6OZ4

Entry DOI	10.2210/pdb6oz4/pdb
Descriptor	Envelope glycoprotein gp160, Envelope glycoprotein gp41, N49P6 antibody Fab heavy chain, ... (9 entities in total)
Functional Keywords	hiv-1 envelop trimer, gp120, gp41, viral entry, viral protein-immune system complex, type-1 membrane fusion glycoprotein, n49p6, immune system
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	4
Total formula weight	126169.42
Authors	Tolbert, W.D.,Pazgier, M. (deposition date: 2019-05-15, release date: 2020-08-19, Last modification date: 2023-10-11)
Primary citation	Tolbert, W.D.,Nguyen, D.N.,Tehrani, Z.R.,Sajadi, M.M.,Pazgier, M. Near-Pan-neutralizing, Plasma Deconvoluted Antibody N49P6 Mimics Host Receptor CD4 in Its Quaternary Interactions with the HIV-1 Envelope Trimer. Mbio, :e0127421-e0127421, 2021 Cited by PubMed: 34281393 DOI: 10.1128/mBio.01274-21 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.05 Å)

Structure validation