4QT5
Crystal Structure of 3BD10: A Monoclonal Antibody against the TSH Receptor
Summary for 4QT5
| Entry DOI | 10.2210/pdb4qt5/pdb |
| Descriptor | 3BD10 mouse monoclonal antibody, light chain, 3BD10 mouse monoclonal antibody, heavy chain (3 entities in total) |
| Functional Keywords | graves disease, antibody, tsh receptor, thyroid, immune system |
| Biological source | Mus musculus More |
| Total number of polymer chains | 4 |
| Total formula weight | 93494.09 |
| Authors | Hubbard, P.A.,Chen, C.R.,McLachlan, S.M.,Rapoport, B.,Murali, R. (deposition date: 2014-07-07, release date: 2015-04-01, Last modification date: 2023-09-20) |
| Primary citation | Chen, C.R.,Hubbard, P.A.,Salazar, L.M.,McLachlan, S.M.,Murali, R.,Rapoport, B. Crystal structure of a TSH receptor monoclonal antibody: insight into Graves' disease pathogenesis. Mol.Endocrinol., 29:99-107, 2015 Cited by PubMed: 25419797DOI: 10.1210/me.2014-1257 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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