4GXU

Crystal structure of antibody 1F1 bound to the 1918 influenza hemagglutinin

Summary for 4GXU

Entry DOI	10.2210/pdb4gxu/pdb
Related	4GXV 4GXX
Descriptor	Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, Antibody 1F1, heavy chain, ... (6 entities in total)
Functional Keywords	viral fusion protein, immunoglobulin, virus attachment and entry, immune recognition, viral protein-immune system complex, viral protein/immune system
Biological source	Influenza A virus More
Total number of polymer chains	24
Total formula weight	631668.28
Authors	Ekiert, D.C.,Wilson, I.A. (deposition date: 2012-09-04, release date: 2012-12-19, Last modification date: 2023-09-13)
Primary citation	Tsibane, T.,Ekiert, D.C.,Krause, J.C.,Martinez, O.,Crowe, J.E.,Wilson, I.A.,Basler, C.F. Influenza Human Monoclonal Antibody 1F1 Interacts with Three Major Antigenic Sites and Residues Mediating Human Receptor Specificity in H1N1 Viruses. Plos Pathog., 8:e1003067-e1003067, 2012 Cited by PubMed: 23236279 DOI: 10.1371/journal.ppat.1003067 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.294 Å)

Structure validation