7FCP

Crystallographic structure of two neutralizing antibodies in complex with SARS-CoV-2 spike receptor-binding Domain (RBD)

Summary for 7FCP

• Entry DOI: 10.2210/pdb7fcp/pdb
• Descriptor: Spike protein S1, P14-44 antibody Fab fragment heavy chain, P14-44 antibody Fab fragment light chain, ... (9 entities in total)
• Functional Keywords: sars-cov-2, rbd, neutralizing antibodies, antiviral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 5
• Total formula weight: 127655.13

Authors

Zheng, P.,Jin, T. (deposition date: 2021-07-15, release date: 2022-06-15, Last modification date: 2023-11-29)

• Primary citation: Zou, J.,Li, L.,Zheng, P.,Liang, W.,Hu, S.,Zhou, S.,Wang, Y.,Zhao, J.,Yuan, D.,Liu, L.,Wu, D.,Xu, M.,Zhang, F.,Zhu, M.,Wu, Z.,Cao, X.,Ni, M.,Ling, X.,Wu, Y.,Kuang, Z.,Hu, M.,Li, J.,Li, X.,Guo, X.,Xu, T.,Jiang, H.,Gao, C.,Yu, M.,Liu, J.,Zhong, N.,Zhou, J.,Huang, J.A.,Jin, T.,He, J.; Ultrapotent neutralizing antibodies against SARS-CoV-2 with a high degree of mutation resistance.; J.Clin.Invest., 132:-, 2022; PubMed: 35108220; DOI: 10.1172/JCI154987

Experimental method

X-RAY DIFFRACTION (2.4 Å)