7FCP
Crystallographic structure of two neutralizing antibodies in complex with SARS-CoV-2 spike receptor-binding Domain (RBD)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Spike protein S1 | polymer | 277 | 30940.7 | 1 | UniProt (P0DTC2) Pfam (PF09408) Pfam (PF19209) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
2 | H | P14-44 antibody Fab fragment heavy chain | polymer | 235 | 25477.5 | 1 | Homo sapiens | ||
3 | L | P14-44 antibody Fab fragment light chain | polymer | 216 | 22858.2 | 1 | Homo sapiens | ||
4 | B | P5-22 antibody Fab fragment heavy chain | polymer | 227 | 24304.2 | 1 | Homo sapiens | ||
5 | D | P5-22 antibody Fab fragment light chain | polymer | 214 | 23547.1 | 1 | Homo sapiens | ||
6 | A | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
7 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
8 | H, D | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
9 | water | water | 18.0 | 589 | Chemie (HOH) |
Sequence modifications
A: 321 - 591 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Val 319 | - | expression tag |
Asp 320 | - | expression tag |
Ser 592 | - | expression tag |
Arg 593 | - | expression tag |
Gly 594 | - | expression tag |
Ser 595 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 127127.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 527.5 | |
All* | Total formula weight | 127655.1 |