7CHY
Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26
Summary for 7CHY
Entry DOI | 10.2210/pdb7chy/pdb |
Descriptor | light chain of antibody binding fragment of IgG26, heavy chain of antibody binding fragment of IgG26, Interleukin-1 beta, ... (4 entities in total) |
Functional Keywords | complex, antibody, interleukin-1beta, immunosuppressant |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 66483.53 |
Authors | Lee, C.C.,Wang, A.H.J.,Kuo, W.C. (deposition date: 2020-07-06, release date: 2021-01-13, Last modification date: 2023-11-29) |
Primary citation | Kuo, W.C.,Lee, C.C.,Chang, Y.W.,Pang, W.,Chen, H.S.,Hou, S.C.,Lo, S.Y.,Yang, A.S.,Wang, A.H. Structure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP. J.Mol.Biol., 433:166766-166766, 2020 Cited by PubMed: 33359099DOI: 10.1016/j.jmb.2020.166766 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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