3TPK

Crystal structure of the oligomer-specific KW1 antibody fragment

Summary for 3TPK

Entry DOI	10.2210/pdb3tpk/pdb
Descriptor	Immunoglobulin heavy chain antibody variable domain KW1, BENZAMIDINE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	immunoglobulin heavy chain domains, vhh, complementarity determining regions, cdr, oligomer-specific, alzheimer's disease, amyloid, immune system
Biological source	Camelidae
Total number of polymer chains	1
Total formula weight	15284.82
Authors	Parthier, C.,Morgado, I.,Stubbs, M.T.,Fandrich, M. (deposition date: 2011-09-08, release date: 2012-07-11, Last modification date: 2023-09-13)
Primary citation	Morgado, I.,Wieligmann, K.,Bereza, M.,Ronicke, R.,Meinhardt, K.,Annamalai, K.,Baumann, M.,Wacker, J.,Hortschansky, P.,Malesevic, M.,Parthier, C.,Mawrin, C.,Schiene-Fischer, C.,Reymann, K.G.,Stubbs, M.T.,Balbach, J.,Gorlach, M.,Horn, U.,Fandrich, M. Molecular basis of beta-amyloid oligomer recognition with a conformational antibody fragment. Proc.Natl.Acad.Sci.USA, 109:12503-12508, 2012 Cited by PubMed: 22814377 DOI: 10.1073/pnas.1206433109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation