6FQ4
 
 | | Structure of Chlamydial virulence factor TarP and vinculin head domain | | Descriptor: | TarP-VBS1, Vinculin | | Authors: | Whitewood, A.J, Singh, A.K, Brown, D.G, Goult, B.T. | | Deposit date: | 2018-02-13 | | Release date: | 2018-05-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | Chlamydial virulence factor TarP mimics talin to disrupt the talin-vinculin complex.
FEBS Lett., 592, 2018
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6FUY
 | | Crystal structure of human full-length vinculin-T12-A974K (residues 1-1066) | | Descriptor: | CALCIUM ION, Vinculin | | Authors: | Chorev, D.S, Volberg, T, Livne, A, Eisenstein, M, Martins, B, Kam, Z, Jockusch, B.M, Medalia, O, Sharon, M, Geiger, B. | | Deposit date: | 2018-02-28 | | Release date: | 2018-03-14 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Conformational states during vinculin unlocking differentially regulate focal adhesion properties.
Sci Rep, 8, 2018
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6DUW
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4E18
 | | Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin | | Descriptor: | Catenin alpha-1, Vinculin | | Authors: | Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I. | | Deposit date: | 2012-03-05 | | Release date: | 2012-05-16 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.403 Å) | | Cite: | Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin
To be Published
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7KTV
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7KTT
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3TJ5
 | | human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-N; residues 412-434) from Rickettsia rickettsii | | Descriptor: | Antigenic heat-stable 120 kDa protein, GLYCEROL, Vinculin | | Authors: | Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T. | | Deposit date: | 2011-08-23 | | Release date: | 2011-09-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
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7KTU
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4EHP
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3TJ6
 | | human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-C; residues 812-835) from Rickettsia rickettsii | | Descriptor: | Antigenic heat-stable 120 kDa protein, Vinculin | | Authors: | Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T. | | Deposit date: | 2011-08-23 | | Release date: | 2011-09-07 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.76 Å) | | Cite: | The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
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5L0G
 | | Human metavinculin MVt Q971R, R975D, T978R mutant (residues 959-1134) in complex with PIP2 | | Descriptor: | Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | Authors: | Chinthalapudi, K, Izard, T. | | Deposit date: | 2016-07-27 | | Release date: | 2016-08-31 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5L0D
 | | Human Metavinculin(residues 959-1130) in complex with PIP2 | | Descriptor: | Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | Authors: | Chinthalapudi, K, Izard, T. | | Deposit date: | 2016-07-27 | | Release date: | 2016-08-31 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5L0H
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5L0I
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5L0J
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1XWJ
 | | Vinculin head (1-258) in complex with the talin vinculin binding site 3 (1945-1969) | | Descriptor: | Talin, Vinculin | | Authors: | Gingras, A.R, Papagrigoriou, E, Barsukov, I.L, Critchley, D.R, Emsley, J. | | Deposit date: | 2004-11-01 | | Release date: | 2005-10-11 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod
Biochemistry, 45, 2006
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1ZW3
 | | Vinculin Head (0-258) in Complex with the Talin Rod residues 1630-1652 | | Descriptor: | Talin 1, Vinculin | | Authors: | Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J. | | Deposit date: | 2005-06-03 | | Release date: | 2005-09-20 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
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1ZVZ
 | | Vinculin Head (0-258) in Complex with the Talin Rod Residue 820-844 | | Descriptor: | Talin 1, Vinculin | | Authors: | Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J. | | Deposit date: | 2005-06-03 | | Release date: | 2005-09-20 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
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1ZW2
 | | Vinculin Head (0-258) in Complex with the Talin Rod residues 2345-2369 | | Descriptor: | Vinculin, talin | | Authors: | Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J. | | Deposit date: | 2005-06-03 | | Release date: | 2005-09-20 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
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1YDI
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1RKC
 | | Human vinculin head (1-258) in complex with talin's vinculin binding site 3 (residues 1944-1969) | | Descriptor: | Talin, Vinculin | | Authors: | Izard, T, Evans, G, Borgon, R.A, Rush, C.L, Bricogne, G, Bois, P.R. | | Deposit date: | 2003-11-21 | | Release date: | 2004-01-13 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Vinculin activation by talin through helical bundle conversion
Nature, 427, 2004
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1TR2
 | | Crystal structure of human full-length vinculin (residues 1-1066) | | Descriptor: | VINCULIN ISOFORM 1 | | Authors: | Borgon, R.A, Vonrhein, C, Bricogne, G, Bois, P.R, Izard, T. | | Deposit date: | 2004-06-19 | | Release date: | 2005-11-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal Structure of Human Vinculin
Structure, 12, 2004
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1T01
 | | Vinculin complexed with the VBS1 helix from talin | | Descriptor: | Talin 1, unnamed protein product | | Authors: | Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J. | | Deposit date: | 2004-04-07 | | Release date: | 2004-08-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
Embo J., 23, 2004
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1ST6
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1SYQ
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