6DUW
Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant
Summary for 6DUW
Entry DOI | 10.2210/pdb6duw/pdb |
Descriptor | Catenin alpha-2 (2 entities in total) |
Functional Keywords | five-helix bundle, f-actin-binding, mechanosensor, cell adhesion |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 28120.34 |
Authors | Ishiyama, N.,Ikura, M. (deposition date: 2018-06-22, release date: 2018-12-19, Last modification date: 2023-10-11) |
Primary citation | Ishiyama, N.,Sarpal, R.,Wood, M.N.,Barrick, S.K.,Nishikawa, T.,Hayashi, H.,Kobb, A.B.,Flozak, A.S.,Yemelyanov, A.,Fernandez-Gonzalez, R.,Yonemura, S.,Leckband, D.E.,Gottardi, C.J.,Tepass, U.,Ikura, M. Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions. Nat Commun, 9:5121-5121, 2018 Cited by PubMed: 30504777DOI: 10.1038/s41467-018-07481-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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