7KTU

Cryogenic electron microscopy model of full-length human metavinculin H1'-parallel conformation 1

Summary for 7KTU

• Entry DOI: 10.2210/pdb7ktu/pdb
• Related: 1TR2
• EMDB information: 23029 23030 23031 23032
• Descriptor: metavinculin (1 entity in total)
• Functional Keywords: actin, adaptor protein, cadherin, cancer, catenin, cell adhesion, cell junction, cell migration, cell signaling, focal adhesions, heart failure, inositol phospholipid, integrin, plasma membrane, skeletal muscle, smooth muscle
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 125061.50

Authors

Izard, T.,Rangarajan, E.S. (deposition date: 2020-11-24, release date: 2021-01-27, Last modification date: 2024-03-06)

• Primary citation: Rangarajan, E.S.,Izard, T.; The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain.; Int J Mol Sci, 22:-, 2021; PubMed: 33440717; DOI: 10.3390/ijms22020645

Experimental method

ELECTRON MICROSCOPY (4.15 Å)