Summary for 5L0G
Descriptor | Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (3 entities in total) |
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Functional Keywords | 5-helix bundle, cytoskelatal protein, phospholipids, cell adhesion, structural protein |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane ; Peripheral membrane protein ; Cytoplasmic side P18206 |
Total number of polymer chains | 4 |
Total molecular weight | 80144.12 |
Authors | Chinthalapudi, K.,Izard, T. (deposition date: 2016-07-27, release date: 2016-08-31, Last modification date: 2017-11-01) |
Primary citation | Chinthalapudi, K.,Rangarajan, E.S.,Brown, D.T.,Izard, T. Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization. Proc.Natl.Acad.Sci.USA, 113:9539-9544, 2016 PubMed: 27503891 (PDB entries with the same primary citation) DOI: 10.1073/pnas.1600702113 ![]() |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |