5L0G

Human metavinculin MVt Q971R, R975D, T978R mutant (residues 959-1134) in complex with PIP2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Vinculin	polymer	176	19662.7	4	UniProt (P18206) Pfam (PF01044) In PDB	Homo sapiens (Human)	Metavinculin,MV
2	B, C	[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate	non-polymer		746.6	2	Chemie (PIO)
3		water	water		18.0	46	Chemie (HOH)

Sequence modifications

A, B, C, D: 959 - 1134 (UniProt: P18206)

PDB	External Database	Details
Arg 971	Gln 971	engineered mutation
Asp 975	Arg 975	engineered mutation
Arg 978	Thr 978	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	78651.0
Non-Polymers*	Number of molecules	2
	Total formula weight	1493.1
All*	Total formula weight	80144.1

*Water molecules are not included.