2JZI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jzi by Molmil](/molmil-images/mine/2jzi) | |
3V79
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3v79 by Molmil](/molmil-images/mine/3v79) | Structure of human Notch1 transcription complex including CSL, RAM, ANK, and MAML-1 on HES-1 promoter DNA sequence | Descriptor: | DNA 5'-D(*GP*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*AP*AP*A)-3', DNA 5'-D(*TP*TP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*TP*AP*AP*C)-3', Mastermind-like protein 1, ... | Authors: | Nam, Y, Sliz, P, Blacklow, S. | Deposit date: | 2011-12-20 | Release date: | 2012-02-15 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.85 Å) | Cite: | Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes. Structure, 20, 2012
|
|
3UV9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uv9 by Molmil](/molmil-images/mine/3uv9) | Structure of the rhesus monkey TRIM5alpha deltav1 PRYSPRY domain | Descriptor: | Tripartite motif-containing protein 5 | Authors: | Biris, N, Yang, Y, Taylor, A.B, Tomashevskii, A, Guo, M, Hart, P.J, Diaz-Griffero, F, Ivanov, D. | Deposit date: | 2011-11-29 | Release date: | 2012-08-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.549 Å) | Cite: | Structure of the rhesus monkey TRIM5alpha PRYSPRY domain, the HIV capsid recognition module. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3V1B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3v1b by Molmil](/molmil-images/mine/3v1b) | Crystal structure of de novo designed MID1-apo2 | Descriptor: | Computational design, MID1-apo2, GLYCEROL | Authors: | Der, B.S, Machius, M, Miley, M.J, Kuhlman, B. | Deposit date: | 2011-12-09 | Release date: | 2012-01-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer. J.Am.Chem.Soc., 134, 2012
|
|
2CXA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cxa by Molmil](/molmil-images/mine/2cxa) | Crystal structure of Leucyl/phenylalanyl-tRNA protein transferase from Escherichia coli | Descriptor: | Leucyl/phenylalanyl-tRNA-protein transferase | Authors: | Kato-Murayama, M, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-06-28 | Release date: | 2005-12-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The crystal structure of leucyl/phenylalanyl-tRNA-protein transferase from Escherichia coli Protein Sci., 16, 2007
|
|
1WZE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wze by Molmil](/molmil-images/mine/1wze) | |
6S5B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s5b by Molmil](/molmil-images/mine/6s5b) | |
6UMJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6umj by Molmil](/molmil-images/mine/6umj) | Crystal structure of erenumab Fab-c | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,3-BUTANEDIOL, erenumab Fab heavy chain, ... | Authors: | Mohr, C. | Deposit date: | 2019-10-09 | Release date: | 2020-02-12 | Last modified: | 2020-02-26 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab). Cell Rep, 30, 2020
|
|
6UMG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6umg by Molmil](/molmil-images/mine/6umg) | Crystal structure of erenumab Fab bound to the extracellular domain of CGRP receptor | Descriptor: | Calcitonin gene-related peptide type 1 receptor, Receptor activity-modifying protein 1, erenumab Fab heavy chain, ... | Authors: | Mohr, C. | Deposit date: | 2019-10-09 | Release date: | 2020-02-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab). Cell Rep, 30, 2020
|
|
6M0A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m0a by Molmil](/molmil-images/mine/6m0a) | The heme-bound structure of the chloroplast protein At3g03890 | Descriptor: | AT3G03890 protein, AZIDE ION, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Wang, J, Liu, L. | Deposit date: | 2020-02-20 | Release date: | 2020-12-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Arabidopsis locus AT3G03890 encodes a dimeric beta-barrel protein implicated in heme degradation. Biochem.J., 2020
|
|
6S7R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s7r by Molmil](/molmil-images/mine/6s7r) | |
2JO8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jo8 by Molmil](/molmil-images/mine/2jo8) | Solution structure of C-terminal domain of human mammalian sterile 20-like kinase 1 (MST1) | Descriptor: | Serine/threonine-protein kinase 4 | Authors: | Hwang, E, Ryu, K.-S, Paakkonen, K, Guntert, P, Cheong, H.-K, Lim, D.-S, Lee, J.O, Jeon, Y.H, Cheong, C. | Deposit date: | 2007-02-26 | Release date: | 2007-05-15 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
5I72
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5i72 by Molmil](/molmil-images/mine/5i72) | Crystal structure of the oligomeric form of the Lassa virus matrix protein Z | Descriptor: | RING finger protein Z, ZINC ION | Authors: | Hastie, K, Zandonatti, M, Liu, T, Li, S, Woods Jr, V, Saphire, E.O. | Deposit date: | 2016-02-16 | Release date: | 2016-03-09 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of the Oligomeric Form of Lassa Virus Matrix Protein Z. J.Virol., 90, 2016
|
|
6M3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m3d by Molmil](/molmil-images/mine/6m3d) | X-ray crystal structure of tandemly connected engrailed homeodomains (EHD) with R53A mutations and DNA complex | Descriptor: | DNA (5'-D(*GP*GP*AP*TP*TP*AP*GP*GP*AP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*TP*CP*CP*TP*AP*AP*TP*CP*C)-3'), SODIUM ION, ... | Authors: | Sunami, T, Hirano, Y, Tamada, T, Kono, H. | Deposit date: | 2020-03-03 | Release date: | 2020-09-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis for designing an array of engrailed homeodomains. Acta Crystallogr D Struct Biol, 76, 2020
|
|
7JRP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jrp by Molmil](/molmil-images/mine/7jrp) | Plant Mitochondrial complex SC III2+IV from Vigna radiata | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Alpha-MPP, ... | Authors: | Maldonado, M, Letts, J.A. | Deposit date: | 2020-08-12 | Release date: | 2021-01-20 | Last modified: | 2021-02-03 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Atomic structures of respiratory complex III 2 , complex IV, and supercomplex III 2 -IV from vascular plants. Elife, 10, 2021
|
|
6UMA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uma by Molmil](/molmil-images/mine/6uma) | |
6UMB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6umb by Molmil](/molmil-images/mine/6umb) | |
2JUN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jun by Molmil](/molmil-images/mine/2jun) | Structure of the MID1 tandem B-boxes reveals an interaction reminiscent of intermolecular RING heterodimers | Descriptor: | Midline-1, ZINC ION | Authors: | Tao, H, Singireddy, S, Jakkidi, M, Simmons, B.N, Short, K.M, Cox, T.C, Massiah, M.A. | Deposit date: | 2007-08-31 | Release date: | 2008-03-04 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of the MID1 Tandem B-Boxes Reveals an Interaction Reminiscent of Intermolecular Ring Heterodimers Biochemistry, 47, 2008
|
|
6M90
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m90 by Molmil](/molmil-images/mine/6m90) | Monophosphorylated pSer33 b-Catenin peptide, b-TrCP/Skp1, NRX-2776 ternary complex | Descriptor: | 2-(2-fluorophenoxy)-3-{[2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carbonyl]amino}benzoic acid, Catenin beta-1, F-box/WD repeat-containing protein 1A, ... | Authors: | Simonetta, K.R, Clifton, M.C, Walter, R.L, Ranieri, G.M, Carter, J.J. | Deposit date: | 2018-08-22 | Release date: | 2019-04-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nat Commun, 10, 2019
|
|
7ZH4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zh4 by Molmil](/molmil-images/mine/7zh4) | USP1 bound to ML323 and ubiquitin conjugated to FANCD2 (focused refinement) | Descriptor: | 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-[[4-(1,2,3-triazol-1-yl)phenyl]methyl]pyrimidin-4-amine, Ubiquitin carboxyl-terminal hydrolase 1, Ubiquitin-60S ribosomal protein L40, ... | Authors: | Rennie, M.L, Walden, H. | Deposit date: | 2022-04-05 | Release date: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (2.49 Å) | Cite: | Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Sci Adv, 8, 2022
|
|
6LPT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lpt by Molmil](/molmil-images/mine/6lpt) | Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-lactate (D-LAC) | Descriptor: | D-2-hydroxyglutarate dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Yang, J, Zhu, H, Ding, J. | Deposit date: | 2020-01-12 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.621 Å) | Cite: | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations. Cell Discov, 7, 2021
|
|
6MCQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mcq by Molmil](/molmil-images/mine/6mcq) | L. pneumophila effector kinase LegK7 in complex with human MOB1A | Descriptor: | DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, LegK7, ... | Authors: | Beyrakhova, K.A, Xu, C, Boniecki, M.T, Cygler, M. | Deposit date: | 2018-09-01 | Release date: | 2019-09-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6MDP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mdp by Molmil](/molmil-images/mine/6mdp) | The D1 and D2 domain rings of NSF engaging the SNAP-25 N-terminus within the 20S supercomplex (focused refinement on D1/D2 rings, class 2) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Synaptosomal-associated protein 25, ... | Authors: | White, K.I, Zhao, M, Brunger, A.T. | Deposit date: | 2018-09-04 | Release date: | 2018-09-19 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural principles of SNARE complex recognition by the AAA+ protein NSF. Elife, 7, 2018
|
|
6A9T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6a9t by Molmil](/molmil-images/mine/6a9t) | Crystal structure of Icp55 from Saccharomyces cerevisiae (N-terminal 58 residues deletion) | Descriptor: | GLYCINE, Intermediate cleaving peptidase 55, MANGANESE (II) ION, ... | Authors: | Singh, R, Kumar, A, Goyal, V.D, Makde, R.D. | Deposit date: | 2018-07-16 | Release date: | 2019-01-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structures and biochemical analyses of intermediate cleavage peptidase: role of dynamics in enzymatic function. FEBS Lett., 593, 2019
|
|
6AA7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6aa7 by Molmil](/molmil-images/mine/6aa7) | |