PDB: 503 resultsInfo pagesStatus searchChemie searchBIRD

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2WKE	Crystal structure of the Actinomadura R39 DD-peptidase inhibited by 6- beta-iodopenicillanate. Descriptor: (3S)-2,2-dimethyl-3,4-dihydro-2H-1,4-thiazine-3,6-dicarboxylic acid, COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, ... Authors: Sauvage, E, Herman, R, Kerff, F, Charlier, P. Deposit date: 2009-06-10 Release date: 2009-12-01 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Basis of the Inhibition of Class a Beta-Lactamases and Penicillin-Binding Proteins by 6-Beta-Iodopenicillanate. J.Am.Chem.Soc., 131, 2009
2XD5	Structural insights into the catalytic mechanism and the role of Streptococcus pneumoniae PBP1b Descriptor: CHLORIDE ION, N-BENZOYL-D-ALANINE, PENICILLIN-BINDING PROTEIN 1B, ... Authors: Macheboeuf, P, Lemaire, D, Jamin, M, Dideberg, O, Dessen, A. Deposit date: 2010-04-29 Release date: 2010-05-26 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Insights Into the Catalytic Mechanism and the Role of Streptococcus Pneumoniae Pbp1B To be Published
3HUN	Crystal structure of Penicillin binding protein 4 from Staphylococcus aureus COL in complex with Ampicillin Descriptor: (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Penicillin-binding protein 4 Authors: Navratna, V, Gopal, B. Deposit date: 2009-06-15 Release date: 2009-11-10 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Molecular basis for the role of Staphylococcus aureus Penicillin Binding Protein 4 in antimicrobial resistance J.Bacteriol., 2009
3HUM	Crystal structure of Penicillin binding protein 4 from Staphylococcus aureus COL in complex with Cefotaxime Descriptor: (2R)-2-[(1R)-1-({[(2R)-2-amino-2,3-dihydro-1,3-thiazol-4-yl](methoxyimino)acetyl}amino)-2-oxoethyl]-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Penicillin-binding protein 4 Authors: Navratna, V, Gopal, B. Deposit date: 2009-06-15 Release date: 2009-11-10 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Molecular basis for the role of Staphylococcus aureus Penicillin Binding Protein 4 in antimicrobial resistance J.Bacteriol., 2009
2WK0	Crystal structure of the class A beta-lactamase BS3 inhibited by 6- beta-iodopenicillanate. Descriptor: (3S)-2,2-dimethyl-3,4-dihydro-2H-1,4-thiazine-3,6-dicarboxylic acid, BETA-LACTAMASE, CHLORIDE ION, ... Authors: Sauvage, E, Zervosen, A, Dive, G, Herman, R, Kerff, F, Amoroso, A, Fonze, E, Pratt, R.F, Luxen, A, Charlier, P. Deposit date: 2009-06-03 Release date: 2009-12-01 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structural Basis of the Inhibition of Class a Beta-Lactamases and Penicillin-Binding Proteins by 6-Beta-Iodopenicillanate. J.Am.Chem.Soc., 131, 2009
6DZ8	Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (S75C) Descriptor: Penicillin-binding protein 4, ZINC ION Authors: Alexander, J.A.N, Strynadka, N.C.J. Deposit date: 2018-07-03 Release date: 2018-12-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Recognition of Peptidoglycan Fragments by the Transpeptidase PBP4 FromStaphylococcus aureus. Front Microbiol, 9, 2018
7BN9	Crystal Structure of Bacillus subtilis Penicillin Binding Protein 3 Descriptor: Penicillin-binding protein 3 Authors: Rao, V.A, Lewis, R.J. Deposit date: 2021-01-21 Release date: 2022-03-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Cooperation between peptidoglycan transpeptidases and SEDS proteins in Bacillus subtilis cell division To Be Published
5VAT	Haemophilus influenzae LpoA: Monoclinic form (Mon2) with 2 molecules per a.u. Descriptor: Penicillin-binding protein activator LpoA Authors: Saper, M.A, Sathiyamoorthy, K. Deposit date: 2017-03-27 Release date: 2017-09-13 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution. J. Biol. Chem., 292, 2017
3TG9	The crystal structure of penicillin binding protein from Bacillus halodurans Descriptor: Penicillin-binding protein Authors: Zhang, Z, Satyanarayana, L, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, LaFleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) Deposit date: 2011-08-17 Release date: 2011-08-31 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The crystal structure of penicillin binding protein from Bacillus halodurans To be Published
6YN0	Structure of E. coli PBP1b with a FtsN peptide activating transglycosylase activity Descriptor: Cell division protein FtsN, MOENOMYCIN, Penicillin-binding protein 1B Authors: Kerff, F, Terrak, M, Boes, A, Herman, H, Charlier, P. Deposit date: 2020-04-10 Release date: 2020-11-04 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The bacterial cell division protein fragment E FtsN binds to and activates the major peptidoglycan synthase PBP1b. J.Biol.Chem., 295, 2020
3ZVT	Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein Descriptor: 2,6 DIMETHOXYBENZAMIDOBORONIC ACID, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ... Authors: Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. Deposit date: 2011-07-27 Release date: 2012-02-29 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein. J.Am.Chem.Soc., 133, 2011
3ZVW	Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,3-DIMETHYLBUTAN-1-OL, ACETONE, ... Authors: Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. Deposit date: 2011-07-28 Release date: 2012-02-29 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein. J.Am.Chem.Soc., 133, 2011
5KCN	Crystal Structure of full-length LpoA from Haemophilus influenzae at 1.97 angstrom resolution Descriptor: CHLORIDE ION, Penicillin-binding protein activator LpoA Authors: Sathiyamoorthy, K, Saper, M.A. Deposit date: 2016-06-06 Release date: 2017-09-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.965 Å) Cite: Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution. J. Biol. Chem., 292, 2017
5VBG	Crystal Structure of full-length LpoA, Monoclinic form 1, from Haemophilus influenzae Descriptor: CHLORIDE ION, Penicillin-binding protein activator LpoA Authors: Sathiyamoorthy, K, Saper, M.A. Deposit date: 2017-03-29 Release date: 2017-09-13 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution. J. Biol. Chem., 292, 2017
1VQQ	Structure of Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 1.80 A resolution. Descriptor: CADMIUM ION, CHLORIDE ION, penicillin-binding protein mecA, ... Authors: Lim, D, Strynadka, N.C.J. Deposit date: 2004-12-17 Release date: 2004-12-28 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus. Nat.Struct.Biol., 9, 2002
1MRU	Intracellular Ser/Thr protein kinase domain of Mycobacterium tuberculosis PknB. Descriptor: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Probable serine/threonine-protein kinase pknB Authors: Young, T.A, Delagoutte, B, Endrizzi, J.A, Alber, T, TB Structural Genomics Consortium (TBSGC) Deposit date: 2002-09-18 Release date: 2003-02-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3 Å) Cite: Structure of Mycobacterium tuberculosis PknB supports a universal activation mechanism for Ser/Thr protein kinases. Nat.Struct.Biol., 10, 2003
2Y59	Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein Descriptor: D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, SULFATE ION, ... Authors: Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. Deposit date: 2011-01-12 Release date: 2011-07-27 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein. J.Am.Chem.Soc., 133, 2011
2Y55	Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein Descriptor: ACETONE, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ... Authors: Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. Deposit date: 2011-01-12 Release date: 2011-07-27 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein. J.Am.Chem.Soc., 133, 2011
2Y4A	Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein Descriptor: D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, SULFATE ION, ... Authors: Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. Deposit date: 2011-01-05 Release date: 2011-07-27 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein. J.Am.Chem.Soc., 133, 2011
1MWR	Structure of SeMet Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r (trigonal form) at 2.45 A resolution. Descriptor: CADMIUM ION, CHLORIDE ION, penicillin-binding protein 2a Authors: Lim, D.C, Strynadka, N.C.J. Deposit date: 2002-10-01 Release date: 2002-11-06 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus. Nat.Struct.Biol., 9, 2002
7V1Z	human Serine beta-lactamase-like protein LACTB Descriptor: Serine beta-lactamase-like protein LACTB, mitochondrial Authors: Zhang, M.H, Yang, M.J. Deposit date: 2021-08-07 Release date: 2022-02-16 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (2.98 Å) Cite: Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB. Structure, 30, 2022
7V21	human Serine beta-lactamase-like protein LACTB truncation variant Descriptor: Serine beta-lactamase-like protein LACTB, mitochondrial Authors: Zhang, M.H, Yang, M.J. Deposit date: 2021-08-07 Release date: 2022-02-16 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.08 Å) Cite: Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB. Structure, 30, 2022
7V1Y	Serine beta-lactamase-like protein LACTB in complex with inhibitor Descriptor: ALA-ALA-B3S, Serine beta-lactamase-like protein LACTB, mitochondrial Authors: Zhang, M.H, Yang, M.J. Deposit date: 2021-08-07 Release date: 2022-02-16 Last modified: 2023-11-15 Method: ELECTRON MICROSCOPY (2.82 Å) Cite: Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB. Structure, 30, 2022
1MWS	Structure of nitrocefin acyl-Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 2.00 A resolution. Descriptor: CADMIUM ION, CHLORIDE ION, penicillin-binding protein 2a Authors: Lim, D.C, Strynadka, N.C.J. Deposit date: 2002-10-01 Release date: 2002-11-06 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus. Nat.Struct.Biol., 9, 2002
5E12	Crystal Structure of PASTA Domains 2, 3 and 4 of Mycobacterium tuberculosis Protein Kinase B Descriptor: CITRATE ANION, Serine/threonine-protein kinase PknB Authors: Prigozhin, D.M, TB Structural Genomics Consortium (TBSGC) Deposit date: 2015-09-29 Release date: 2016-09-14 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.208 Å) Cite: Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site. J.Biol.Chem., 291, 2016

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