2WKE
Crystal structure of the Actinomadura R39 DD-peptidase inhibited by 6- beta-iodopenicillanate.
Summary for 2WKE
Entry DOI | 10.2210/pdb2wke/pdb |
Related | 1W79 1W8Q 1W8Y 2VGJ 2VGK 2WIX |
Descriptor | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, (3S)-2,2-dimethyl-3,4-dihydro-2H-1,4-thiazine-3,6-dicarboxylic acid, SULFATE ION, ... (5 entities in total) |
Functional Keywords | hydrolase, antibiotic resistance, actinomadura, penicillin binding, iodopenicillanate |
Biological source | ACTINOMADURA SP. |
Cellular location | Secreted: P39045 |
Total number of polymer chains | 4 |
Total formula weight | 194203.31 |
Authors | Sauvage, E.,Herman, R.,Kerff, F.,Charlier, P. (deposition date: 2009-06-10, release date: 2009-12-01, Last modification date: 2023-12-13) |
Primary citation | Sauvage, E.,Zervosen, A.,Dive, G.,Herman, R.,Amoroso, A.,Joris, B.,Fonze, E.,Pratt, R.F.,Luxen, A.,Charlier, P.,Kerff, F. Structural Basis of the Inhibition of Class a Beta-Lactamases and Penicillin-Binding Proteins by 6-Beta-Iodopenicillanate. J.Am.Chem.Soc., 131:15262-, 2009 Cited by PubMed: 19919161DOI: 10.1021/JA9051526 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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