3HUM
Crystal structure of Penicillin binding protein 4 from Staphylococcus aureus COL in complex with Cefotaxime
Summary for 3HUM
| Entry DOI | 10.2210/pdb3hum/pdb |
| Descriptor | Penicillin-binding protein 4, (2R)-2-[(1R)-1-({[(2R)-2-amino-2,3-dihydro-1,3-thiazol-4-yl](methoxyimino)acetyl}amino)-2-oxoethyl]-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid (3 entities in total) |
| Functional Keywords | penicillin binding protein 4, cefotaxime, beta-lactamase, serine type d-ala, d-ala-carboxypeptidase, antibiotics, hydrolase-antibiotics complex, hydrolase/antibiotics |
| Biological source | Staphylococcus aureus |
| Total number of polymer chains | 2 |
| Total formula weight | 102160.78 |
| Authors | Navratna, V.,Gopal, B. (deposition date: 2009-06-15, release date: 2009-11-10, Last modification date: 2023-11-01) |
| Primary citation | Navratna, V.,Nadig, S.,Sood, V.,Prasad, K.,Arakere, G.,Gopal, B. Molecular basis for the role of Staphylococcus aureus Penicillin Binding Protein 4 in antimicrobial resistance J.Bacteriol., 2009 Cited by PubMed: 19854906DOI: 10.1128/JB.00822-09 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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