Crystal Structure of full-length LpoA from Haemophilus influenzae at 1.97 angstrom resolution

Summary for 5KCN

Related3CKM 4P29 5VAT 5VBG
DescriptorPenicillin-binding protein activator LpoA, CHLORIDE ION (3 entities in total)
Functional Keywordsouter membrane lipoprotein, pbp1a, transpeptidase. peptidoglycan, biosynthetic protein
Biological sourceHaemophilus influenzae
Cellular locationCell outer membrane ; Lipid- anchor ; Periplasmic side  P45299
Total number of polymer chains1
Total molecular weight60045.53
Sathiyamoorthy, K.,Saper, M.A. (deposition date: 2016-06-06, release date: 2017-09-13, Last modification date: 2017-11-08)
Primary citation
Sathiyamoorthy, K.,Vijayalakshmi, J.,Tirupati, B.,Fan, L.,Saper, M.A.
Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution.
J. Biol. Chem., 292:17626-17642, 2017
PubMed: 28887305 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M117.804997
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.215200.2%11.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution