3HUN

Crystal structure of Penicillin binding protein 4 from Staphylococcus aureus COL in complex with Ampicillin

Summary for 3HUN

Entry DOI	10.2210/pdb3hun/pdb
Descriptor	Penicillin-binding protein 4, (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid (3 entities in total)
Functional Keywords	penicillin binding protein 4, ampicillin, beta-lactamase, serine type d-ala, d-ala-carboxypeptidase, antibiotics, hydrolase-antibiotics complex, hydrolase/antibiotics
Biological source	Staphylococcus aureus
Total number of polymer chains	2
Total formula weight	102092.70
Authors	Navratna, V.,Gopal, B. (deposition date: 2009-06-15, release date: 2009-11-10, Last modification date: 2023-11-01)
Primary citation	Navratna, V.,Nadig, S.,Sood, V.,Prasad, K.,Arakere, G.,Gopal, B. Molecular basis for the role of Staphylococcus aureus Penicillin Binding Protein 4 in antimicrobial resistance J.Bacteriol., 2009 Cited by PubMed: 19854906 DOI: 10.1128/JB.00822-09 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation