2Y55
Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein
Summary for 2Y55
Entry DOI | 10.2210/pdb2y55/pdb |
Related | 1W79 1W8Q 1W8Y 2VGJ 2VGK 2WKE 2XDM 2XK1 2XLN 2Y4A 2Y59 2Y5O 2Y5R |
Descriptor | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, PHENYLACETAMIDOMETHYL BORONIC ACID, SULFATE ION, ... (6 entities in total) |
Functional Keywords | hydrolase-inhibitor complex, peptidoglycan, hydrolase |
Biological source | ACTINOMADURA SP. R39 |
Cellular location | Secreted: P39045 |
Total number of polymer chains | 4 |
Total formula weight | 193380.73 |
Authors | Sauvage, E.,Zervosen, A.,Herman, R.,Kerff, F.,Rocaboy, M.,Charlier, P. (deposition date: 2011-01-12, release date: 2011-07-27, Last modification date: 2023-12-20) |
Primary citation | Zervosen, A.,Herman, R.,Kerff, F.,Herman, A.,Bouillez, A.,Prati, F.,Pratt, R.F.,Frere, J.M.,Joris, B.,Luxen, A.,Charlier, P.,Sauvage, E. Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein. J.Am.Chem.Soc., 133:10839-, 2011 Cited by PubMed: 21574608DOI: 10.1021/JA200696Y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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