2XDM
Crystal structure of a complex between Actinomadura R39 DD peptidase and a peptidoglycan mimetic boronate inhibitor
Summary for 2XDM
Entry DOI | 10.2210/pdb2xdm/pdb |
Related | 1W79 1W8Q 1W8Y 2VGJ 2VGK 2WIX 2WKE |
Descriptor | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, SULFATE ION, COBALT (II) ION, ... (6 entities in total) |
Functional Keywords | hydrolase-inhibitor complex, boronic acid, peptidoglycan, hydrolase, hydrolase/inhibitor |
Biological source | ACTINOMADURA |
Cellular location | Secreted: P39045 |
Total number of polymer chains | 4 |
Total formula weight | 193466.40 |
Authors | Rocaboy, M.,Sauvage, E.,Herman, R.,Kerff, F.,Charlier, P. (deposition date: 2010-05-04, release date: 2010-07-21, Last modification date: 2023-12-20) |
Primary citation | Dzhekieva, L.,Rocaboy, M.,Kerff, F.,Charlier, P.,Sauvage, E.,Pratt, R.F. Crystal Structure of a Complex between the Actinomadura R39 Dd-Peptidase and a Peptidoglycan- Mimetic Boronate Inhibitor: Interpretation of a Transition State Analogue in Terms of Catalytic Mechanism. Biochemistry, 49:6411-, 2010 Cited by PubMed: 20608745DOI: 10.1021/BI100757C PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report