2XK1
Crystal structure of a complex between Actinomadura R39 DD-peptidase and a boronate inhibitor
Summary for 2XK1
Entry DOI | 10.2210/pdb2xk1/pdb |
Related | 1W79 1W8Q 1W8Y 2VGJ 2VGK 2WKE 2XDM |
Descriptor | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, [(1S)-1-{[(2-benzylphenyl)carbonyl]amino}ethyl](trihydroxy)borate(1-), SULFATE ION, ... (5 entities in total) |
Functional Keywords | hydrolase, peptidoglycan |
Biological source | ACTINOMADURA SP |
Cellular location | Secreted: P39045 |
Total number of polymer chains | 4 |
Total formula weight | 193561.30 |
Authors | Sauvage, E.,Herman, R.,Kerff, F.,Rocaboy, M.,Charlier, P. (deposition date: 2010-07-07, release date: 2011-01-26, Last modification date: 2023-12-20) |
Primary citation | Woon, E.C.Y.,Zervosen, A.,Sauvage, E.,Simmons, K.J.,Ivec, M.,Inglis, S.R.,Fishwick, C.W.G.,Gobec, S.,Charlier, P.,Luxen, A.,Schofield, C.J. Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors Acs Med.Chem.Lett., 2:219-, 2011 Cited by PubMed: 24900305DOI: 10.1021/ML100260X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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