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PDB: 47 results

7MSO
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BU of 7mso by Molmil
Crystal Structure of Polo Box Domain in Complex with Cyclic Peptide Inhibitor
Descriptor: Cyclic Peptide Inhibitor ZO1-GLN-SER-TPO-45W-MLL, Serine/threonine-protein kinase PLK1
Authors:Lim, D.C, Yaffe, M.B.
Deposit date:2021-05-11
Release date:2022-03-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Novel Macrocyclic Peptidomimetics Targeting the Polo-Box Domain of Polo-Like Kinase 1.
J.Med.Chem., 65, 2022
3FVH
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BU of 3fvh by Molmil
Polo-like kinase 1 Polo box domain in complex with Ac-LHSpTA-NH2 peptide
Descriptor: Acetyl-Leu-His-Ser-phosphoThr-Ala-NH2 peptide, Serine/threonine-protein kinase PLK1
Authors:Lim, D.C, Yaffe, M.B.
Deposit date:2009-01-15
Release date:2009-08-04
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1
Nat.Struct.Mol.Biol., 16, 2009
3C5L
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BU of 3c5l by Molmil
Polo-like kinase 1 Polo box domain in complex with PPHSpT peptide
Descriptor: Peptide, Serine/threonine-protein kinase PLK1
Authors:Lim, D.C, Yaffe, M.B.
Deposit date:2008-01-31
Release date:2009-02-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.
Nat.Struct.Mol.Biol., 16, 2009
8GSV
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BU of 8gsv by Molmil
Crystal structure of human BAK in complex with the Pxt1 BH3 domain
Descriptor: Bcl-2 homologous antagonist/killer, Peroxisomal testis-specific protein 1
Authors:Lim, D, Ku, B.
Deposit date:2022-09-07
Release date:2023-05-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for proapoptotic activation of Bak by the noncanonical BH3-only protein Pxt1.
Plos Biol., 21, 2023
7WJH
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BU of 7wjh by Molmil
Crystal structure of Bcl-xL bound to the BH3 domain of human Pxt1
Descriptor: Bcl-2-like protein 1, MAGNESIUM ION, Peroxisomal testis-specific protein 1, ...
Authors:Lim, D, Ku, B.
Deposit date:2022-01-06
Release date:2022-09-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Structural and biochemical analyses of Bcl-xL in complex with the BH3 domain of peroxisomal testis-specific 1.
Biochem.Biophys.Res.Commun., 625, 2022
1MWT
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BU of 1mwt by Molmil
Structure of penicillin G acyl-Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 2.45 A resolution.
Descriptor: CADMIUM ION, CHLORIDE ION, OPEN FORM - PENICILLIN G, ...
Authors:Lim, D.C, Strynadka, N.C.J.
Deposit date:2002-10-01
Release date:2002-11-06
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus.
Nat.Struct.Biol., 9, 2002
1MWU
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BU of 1mwu by Molmil
Structure of methicillin acyl-Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 2.60 A resolution.
Descriptor: (2R,4S)-2-[(1R)-1-{[(2,6-dimethoxyphenyl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CADMIUM ION, CHLORIDE ION, ...
Authors:Lim, D.C, Strynadka, N.C.J.
Deposit date:2002-10-01
Release date:2002-11-06
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus.
Nat.Struct.Biol., 9, 2002
1MWR
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BU of 1mwr by Molmil
Structure of SeMet Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r (trigonal form) at 2.45 A resolution.
Descriptor: CADMIUM ION, CHLORIDE ION, penicillin-binding protein 2a
Authors:Lim, D.C, Strynadka, N.C.J.
Deposit date:2002-10-01
Release date:2002-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus.
Nat.Struct.Biol., 9, 2002
1MWS
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BU of 1mws by Molmil
Structure of nitrocefin acyl-Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 2.00 A resolution.
Descriptor: CADMIUM ION, CHLORIDE ION, penicillin-binding protein 2a
Authors:Lim, D.C, Strynadka, N.C.J.
Deposit date:2002-10-01
Release date:2002-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus.
Nat.Struct.Biol., 9, 2002
6VPJ
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BU of 6vpj by Molmil
TPX2 residues 7-20 fused to Aurora A residues 116-389 C247V + C319V double mutant dephosphorylated, and in complex with AMP-PNP
Descriptor: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, TPX2 fragment - Aurora A kinase domain fusion, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose
Authors:Lim, D.C, Yaffe, M.B.
Deposit date:2020-02-03
Release date:2020-08-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Redox priming promotes Aurora A activation during mitosis.
Sci.Signal., 13, 2020
1LNW
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BU of 1lnw by Molmil
CRYSTAL STRUCTURE OF THE MEXR REPRESSOR OF THE MEXAB-OPRM MULTIDRUG EFFLUX OPERON OF PSEUDOMONAS AERUGINOSA
Descriptor: Multidrug resistance operon repressor
Authors:Lim, D.C, Poole, K, Strynadka, N.C.J.
Deposit date:2002-05-03
Release date:2002-09-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the MexR repressor of the mexRAB-oprM multidrug efflux operon of Pseudomonas aeruginosa.
J.Biol.Chem., 277, 2002
1DKM
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BU of 1dkm by Molmil
CRYSTAL STRUCTURE OF ESCHERICHIA COLI PHYTASE AT PH 6.6 WITH HG2+ CATION ACTING AS AN INTERMOLECULAR BRIDGE
Descriptor: MERCURY (II) ION, PHYTASE
Authors:Lim, D, Golovan, S, Forsberg, C.W, Jia, Z.
Deposit date:1999-12-08
Release date:2000-08-02
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structures of Escherichia coli phytase and its complex with phytate.
Nat.Struct.Biol., 7, 2000
1DKQ
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BU of 1dkq by Molmil
CRYSTAL STRUCTURE OF PHYTATE COMPLEX ESCHERICHIA COLI PHYTASE AT PH 5.0. PHYTATE IS BOUND WITH ITS 3-PHOSPHATE IN THE ACTIVE SITE. HG2+ CATION ACTS AS AN INTERMOLECULAR BRIDGE
Descriptor: INOSITOL HEXAKISPHOSPHATE, MERCURY (II) ION, PHYTASE
Authors:Lim, D, Golovan, S, Forsberg, C.W, Jia, Z.
Deposit date:1999-12-08
Release date:2000-08-03
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of Escherichia coli phytase and its complex with phytate.
Nat.Struct.Biol., 7, 2000
1DKL
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BU of 1dkl by Molmil
CRYSTAL STRUCTURE OF ESCHERICHIA COLI PHYTASE AT PH 4.5 (NO LIGAND BOUND)
Descriptor: PHYTASE
Authors:Lim, D, Golovan, S, Forsberg, C.W, Jia, Z.
Deposit date:1999-12-08
Release date:2000-08-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of Escherichia coli phytase and its complex with phytate.
Nat.Struct.Biol., 7, 2000
1DKO
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BU of 1dko by Molmil
CRYSTAL STRUCTURE OF TUNGSTATE COMPLEX OF ESCHERICHIA COLI PHYTASE AT PH 6.6 WITH TUNGSTATE BOUND AT THE ACTIVE SITE AND WITH HG2+ CATION ACTING AS AN INTERMOLECULAR BRIDGE
Descriptor: MERCURY (II) ION, PHYTASE, TUNGSTATE(VI)ION
Authors:Lim, D, Golovan, S, Forsberg, C.W, Jia, Z.
Deposit date:1999-12-08
Release date:2000-08-03
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structures of Escherichia coli phytase and its complex with phytate.
Nat.Struct.Biol., 7, 2000
1DKP
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BU of 1dkp by Molmil
CRYSTAL STRUCTURE OF PHYTATE COMPLEX OF ESCHERICHIA COLI PHYTASE AT PH 6.6. PHYTATE IS BOUND WITH ITS 3-PHOSPHATE IN THE ACTIVE SITE. HG2+ CATION ACTS AS AN INTERMOLECULAR BRIDGE
Descriptor: INOSITOL HEXAKISPHOSPHATE, MERCURY (II) ION, PHYTASE
Authors:Lim, D, Golovan, S, Forsberg, C.W, Jia, Z.
Deposit date:1999-12-08
Release date:2000-08-03
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structures of Escherichia coli phytase and its complex with phytate.
Nat.Struct.Biol., 7, 2000
1DKN
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BU of 1dkn by Molmil
CRYSTAL STRUCTURE OF ESCHERICHIA COLI PHYTASE AT PH 5.0 WITH HG2+ CATION ACTING AS AN INTERMOLECULAR BRIDGE
Descriptor: MERCURY (II) ION, PHYTASE
Authors:Lim, D, Golovan, S, Forsberg, C.W, Jia, Z.
Deposit date:1999-12-08
Release date:2000-08-03
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Escherichia coli phytase and its complex with phytate.
Nat.Struct.Biol., 7, 2000
6VPM
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BU of 6vpm by Molmil
TPX2 residues 7-20 fused to Aurora A residues 116-389 with C290 disulfide bonded to compound 8-34, and in complex with AMP-PNP
Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, MALONIC ACID, ...
Authors:Lim, D.C, Yaffe, M.B.
Deposit date:2020-02-03
Release date:2020-08-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Redox priming promotes Aurora A activation during mitosis.
Sci.Signal., 13, 2020
6VPL
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BU of 6vpl by Molmil
TPX2 residues 7-20 fused to Aurora A residues 116-389 with C290 disulfide bonded to compound 7-80, and in complex with AMP-PNP
Descriptor: GLYCEROL, MAGNESIUM ION, MALONIC ACID, ...
Authors:Lim, D.C, Yaffe, M.B.
Deposit date:2020-02-03
Release date:2020-08-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Redox priming promotes Aurora A activation during mitosis.
Sci.Signal., 13, 2020
6VPG
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BU of 6vpg by Molmil
TPX2 residues 7-20 fused to Aurora A residues 116-389 in complex with AMP-PNP
Descriptor: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
Authors:Lim, D.C, Yaffe, M.B.
Deposit date:2020-02-03
Release date:2020-08-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Redox priming promotes Aurora A activation during mitosis.
Sci.Signal., 13, 2020
6VPI
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BU of 6vpi by Molmil
TPX2 residues 7-20 fused to Aurora A residues 116-389 C247V + D256N + C319V triple mutant disulfide homodimer in complex with AMP-PNP
Descriptor: MAGNESIUM ION, MALONIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Lim, D.C, Yaffe, M.B.
Deposit date:2020-02-03
Release date:2020-08-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Redox priming promotes Aurora A activation during mitosis.
Sci.Signal., 13, 2020
6VPH
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BU of 6vph by Molmil
TPX2 residues 7-20 fused to Aurora A residues 116-389 modified with cacodylate and in complex with AMP-PNP
Descriptor: CHLORIDE ION, DITHIANE DIOL, GLYCEROL, ...
Authors:Lim, D.C, Yaffe, M.B.
Deposit date:2020-02-03
Release date:2020-08-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Redox priming promotes Aurora A activation during mitosis.
Sci.Signal., 13, 2020
1JTD
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BU of 1jtd by Molmil
Crystal structure of beta-lactamase inhibitor protein-II in complex with TEM-1 beta-lactamase
Descriptor: CALCIUM ION, TEM-1 beta-lactamase, beta-lactamase inhibitor protein II
Authors:Lim, D.C, Park, H.U, De Castro, L, Kang, S.G, Lee, H.S, Jensen, S, Lee, K.J, Strynadka, N.C.J.
Deposit date:2001-08-20
Release date:2001-10-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and kinetic analysis of beta-lactamase inhibitor protein-II in complex with TEM-1 beta-lactamase.
Nat.Struct.Biol., 8, 2001
3GMW
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BU of 3gmw by Molmil
Crystal Structure of Beta-Lactamse Inhibitory Protein-I (BLIP-I) in Complex with TEM-1 Beta-Lactamase
Descriptor: B-lactamase, Beta-lactamase inhibitory protein BLIP-I, PHOSPHATE ION
Authors:Lim, D.C, Gretes, M, Strynadka, N.C.J.
Deposit date:2009-03-15
Release date:2009-03-31
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights into positive and negative requirements for protein-protein interactions by crystallographic analysis of the beta-lactamase inhibitory proteins BLIP, BLIP-I, and BLP.
J.Mol.Biol., 389, 2009
3GMV
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Crystal Structure of Beta-Lactamse Inhibitory Protein-I (BLIP-I) in Apo Form
Descriptor: Beta-lactamase inhibitory protein BLIP-I, TRIS(HYDROXYETHYL)AMINOMETHANE
Authors:Lim, D.C, Gretes, M, Strynadka, N.C.J.
Deposit date:2009-03-15
Release date:2009-03-31
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Insights into positive and negative requirements for protein-protein interactions by crystallographic analysis of the beta-lactamase inhibitory proteins BLIP, BLIP-I, and BLP.
J.Mol.Biol., 389, 2009

 

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