8GSV

Crystal structure of human BAK in complex with the Pxt1 BH3 domain

Summary for 8GSV

• Entry DOI: 10.2210/pdb8gsv/pdb
• Descriptor: Bcl-2 homologous antagonist/killer, Peroxisomal testis-specific protein 1 (3 entities in total)
• Functional Keywords: peroxisomal testis-specific 1, pxt1, bak, bh3, apoptosis
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 24
• Total formula weight: 267204.73

Authors

Lim, D.,Ku, B. (deposition date: 2022-09-07, release date: 2023-05-10, Last modification date: 2023-11-29)

• Primary citation: Lim, D.,Choe, S.H.,Jin, S.,Lee, S.,Kim, Y.,Shin, H.C.,Choi, J.S.,Oh, D.B.,Kim, S.J.,Seo, J.,Ku, B.; Structural basis for proapoptotic activation of Bak by the noncanonical BH3-only protein Pxt1.; Plos Biol., 21:e3002156-e3002156, 2023; PubMed: 37315086; DOI: 10.1371/journal.pbio.3002156

Experimental method

X-RAY DIFFRACTION (2.2 Å)